AZT 3'-Azido-2'-deoxythymidine Zidovudine (INN) or azidothymidine (abbreviated to AZT) is an antiretroviral drug, the first antiviral treatment to be approved for use against HIV. It is also sold under the names Retrovir and Retrovis, and as an ingredient in Combivir and Trizivir. Zidovudine - History. Zidovudine was the first drug approved for the treatment of AIDS and HIV infection. Jerome Horowitz first synthesized AZT in 1964, under a US Nat ...

Including:

• Zidovudine - History
• Zidovudine - Treatment
• Zidovudine - Side effects
• Zidovudine - Mode of action
• Zidovudine - Patent Issues

Read more here: » Zidovudine: Encyclopedia - Zidovudine

Zidovudine was the first drug approved for the treatment of AIDS and HIV infection. Jerome Horowitz first synthesized AZT in 1964, under a US National Institutes of Health (NIH) grant. It was originally intended to treat cancer, but failed to show efficacy and had an unacceptably high side effect profile. The drug then faded from view until February 1985, when Samuel Broder, Hiroaki Mitsuya, and Robert Yarchoan, three scientists in the National Cancer Institute (NCI), collaborating with scientists in Burroughs Wellcome Co., started working o ...

See also:

Zidovudine, Zidovudine - History, Zidovudine - Treatment, Zidovudine - Side effects, Zidovudine - Mode of action, Zidovudine - Patent Issues

Read more here: » Zidovudine: Encyclopedia II - Zidovudine - History