Zidovudine - Article Index

Encyclopedia - Zidovudine: Encyclopedia - Zidovudine
AZT 3'-Azido-2'-deoxythymidine Zidovudine (INN) or azidothymidine (abbreviated to AZT) is an antiretroviral drug, the first antiviral tr...   » Read the article

Encyclopedia - Zidovudine: Encyclopedia Ii - Zidovudine - History
Zidovudine was the first drug approved for the treatment of AIDS and HIV infection. Jerome Horowitz first synthesized AZT in 1964, under ...   » Read the article

Encyclopedia - Zidovudine: Encyclopedia Ii - Zidovudine - History
Zidovudine was the first drug approved for the treatment of AIDS and HIV infection. Jerome Horowitz first synthesized AZT in 1964, under ...   » Read the article

Encyclopedia - Atazanavir: Encyclopedia - Atazanavir
Atazanavir (Reyataz®) is an antiretroviral drug which belongs to the class of protease inhibitors (PIs). Antiretrovirals are used in the...   » Read the article

Encyclopedia - Antiretroviral Drug: Encyclopedia - Antiretroviral Drug
Antiretroviral drugs are medications for the treatment of infection by retroviruses, primarily HIV. Different classes of antiretroviral d...   » Read the article

Encyclopedia - Vidarabine: Encyclopedia - Vidarabine
Vidarabine is an anti-viral drug which is active against herpes simplex and varicella zoster viruses. Vidarabine - How the drug was disco...   » Read the article

Encyclopedia - Valaciclovir: Encyclopedia - Valaciclovir
Valaciclovir (INN) or valacyclovir (USAN) is an antiviral drug used in the management of herpes simplex. It is a prodrug, being converted...   » Read the article

Encyclopedia - Atc Code J05: Encyclopedia - Atc Code J05
A section of the Anatomical Therapeutic Chemical Classification System. J Anti-infectives for systemic use ATC code J05 - J05A Direct act...   » Read the article

Encyclopedia - Cidofovir: Encyclopedia - Cidofovir
Cidofovir is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses...   » Read the article

Encyclopedia - Hepatitis: Encyclopedia - Hepatitis
Hepatitis is a gastroenterological disease, featuring inflammation of the liver. The clinical signs and prognosis, as well as the therapy...   » Read the article

Encyclopedia - Antiviral Drug: Encyclopedia - Antiviral Drug
Antiviral drugs are a class of medication used specifically for treating viral infections. Like antibiotics, specific antivirals are used...   » Read the article

Encyclopedia - Didanosine: Encyclopedia Ii - Didanosine - History
Didanosine was developed by Samuel Broder, Hiroaki Mitsuya, and Robert Yarchoan in the National Cancer Institute (NCI). Since the NCI can...   » Read the article

Encyclopedia - Lamivudine: Encyclopedia Ii - Lamivudine - History
Lamivudine was invented by Bernard Belleau and Nghe Nguyen-Ba at the Montreal-based IAF BioChem International, Inc. laboratories in 1989....   » Read the article

Encyclopedia - Interferon: Encyclopedia Ii - Interferon - Pharmacological Uses
Interferon was scarce and expensive until 1980 when the interferon gene was inserted into bacteria using recombinant DNA technology, allo...   » Read the article

Encyclopedia - Vidarabine: Encyclopedia Ii - Vidarabine - How The Drug Was Discovered
In the 1950’s two nucleosides were isolated from the Caribbean sponge Tethya crypta: spongothymidine and spongouridine; which containe...   » Read the article

Encyclopedia - Antiretroviral Drug: Encyclopedia Ii - Antiretroviral Drug - Classes Of Antiretroviral Drugs
Antiretroviral drugs are broadly classified by the phase of the retrovirus life-cyle that the drug inhibits. The following are thus the b...   » Read the article

Encyclopedia - Didanosine: Encyclopedia Ii - Didanosine - Mechanism Of Action
Didanosine (ddI) is a nucleoside analogue of adenosine. It differs from other nucleoside analogues, because it does not have any of the r...   » Read the article

Encyclopedia - Vidarabine: Encyclopedia Ii - Vidarabine - Selectivity
Vidarabine is less susceptible to the development of drug resistant strains than other antivirals such as IDU, and has been used success...   » Read the article

Encyclopedia - Antiretroviral Drug: Encyclopedia Ii - Antiretroviral Drug - Current Treatment Guidelines
Antiretroviral drug treatment guidelines have changed many times. Early recommendations attempted a "hit hard, hit early" approach. A mor...   » Read the article

Encyclopedia - Antiretroviral Drug: Encyclopedia Ii - Antiretroviral Drug - Limitations Of Antiretroviral Drug Therapy
If an HIV infection becomes resistant to standard HAART, there are limited options. One option is to take larger combinations of antiretr...   » Read the article

Encyclopedia - Antiretroviral Drug: Encyclopedia Ii - Antiretroviral Drug - Combination Therapy
The life cycle of HIV can be as short as about 1.5 days: from viral entry into a cell; through replication, assembly, and release of addi...   » Read the article

Encyclopedia - Vidarabine: Encyclopedia Ii - Vidarabine - Mode Of Action
The Mechanism of Action of Vidarabine Vidarabine works by interfering with the synthesis of viral DNA [5]. It is a nucleoside analog a...   » Read the article

Encyclopedia - Vidarabine: Encyclopedia Ii - Vidarabine - Synthesis/preparation/isolation
Vidarabine has been synthesised using E. coli bacterial cells [10], and by using Vorbrüggen glycosylation with a Lewis acid catalyst. T...   » Read the article

Encyclopedia - Vidarabine: Encyclopedia Ii - Vidarabine - Mode Of Resistance
Vidarabine is more toxic and less metabolically stable than many of the other current antivirals such as acyclovir and ganciclovir. Vira...   » Read the article

Encyclopedia - Vidarabine: Encyclopedia Ii - Vidarabine - Current Clinical Indication
Vidarabine is an antiviral, active against herpes viruses, poxviruses, rhabdoviruses, hepadnarviruses and some RNA tumour viruses. A 3% ...   » Read the article