Yanagimachi was born in Japan. He received a BS in zoology in 1952 and a DSc in animal embryology in 1960 from Hokkaido University. He then taught high school for two years because he could not find a research job.
Yanagimachi applied for a post-doctoral position with Dr. M. C. Chang of the Worcester Foundation for Experimental Biology in Shrewsbury, Massachusetts. He got this position and there discovered how to fertilize hamster eggs in the laboratory. This work led to ...
In July 1998 the Yanagimachi laboratory published work in Nature on cloning mice from adult cells. Yanagimachi named the new cloning technique they had created to do this work the "Honolulu technique". The first mouse born was named Cumulina, after the cumulus cells whose nuclei were used to clone her. At the time of the publication of this work over fifty mice spanning three generations had been produced through this technique.
This work was done by an international team of scientists dubbed "Team Yanagimachi" or "Team Yana" f ...
The Yanagimachi lab also studies gene manipulation, cell differentiation, sperm and egg fertilization, and infertility.
It was announced in March 2004 that the Yanagimachi laboratory had helped to produce a live birth of a mammal other than a mouse from freeze-dried sperm. The rabbit kit was born at the University of Connecticut, but soon died because the mother did not care for it. The lab supplied the freeze-dried sperm.[2]
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