 Rare disease - Prevalence: Encyclopedia II - Rare disease - PrevalenceAs a guide, low prevalence is taken as prevalence of less than 5 per 10,000 in the community [1].
The NIH's Office of Rare Diseases states that, "an orphan or rare disease is generally considered to have a prevalence of fewer than 200,000 affected individuals in the United States" [2].
Rare diseases will vary from population to population, as a disease that is rare in some populations may be common in another. This is especially true of some genetic and infectious diseases. For example, cystic fibrosis is a rare genetic ...
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