Encyclopedia - Metformin: Encyclopedia Ii - Metformin - Uses
The main use for metformin is for the treatment of diabetes mellitus, especially when it is concomitant with obesity and insulin resistan...   » Read the article

Encyclopedia - Metformin: Encyclopedia Ii - Metformin - Side-effects
The most serious side effect of metformin is lactic acidosis. However, this complication is rare if the contra-indications are followed, ...   » Read the article

Encyclopedia - Sulfonylurea: Encyclopedia Ii - Sulfonylurea - Uses
Sulfonylureas are used almost exclusively in diabetes mellitus type 2. Other types of diabetes generally do not respond to sulfonylurea t...   » Read the article

Encyclopedia - Sulfonylurea: Encyclopedia Ii - Sulfonylurea - Side-effects And Cautions
Sulfonylureas, as opposed to metformin and the thiazolidinediones, can induce hypoglycemia when insulin production overshoots. It is trea...   » Read the article

Encyclopedia - Sulfonylurea: Encyclopedia Ii - Sulfonylurea - Chemistry
Please see individual members of the class for their chemical structure All sulfonylureas have a central phenyl ring with two branching c...   » Read the article

Encyclopedia - Sulfonylurea: Encyclopedia Ii - Sulfonylurea - Drugs In This Class
First generation: Chlorpropamide Tolbutamide Tolazamide Second generation: Glipizide Gliclazide Glibenclamide Glimepiride Gliquidone ...   » Read the article

Encyclopedia - Sulfonylurea: Encyclopedia Ii - Sulfonylurea - Chemistry
Please see individual members of the class for their chemical structure All sulfonylureas have a central phenyl ring with two branching c...   » Read the article

Encyclopedia - Sulfonylurea: Encyclopedia Ii - Sulfonylurea - Pharmacology
Sulfonylurea - Method of action. Sulfonylureas bind to an ATP-dependent K+ channel on the cell membrane of pancreatic beta cells. This ...   » Read the article

Encyclopedia - Anti-diabetic Drug: Encyclopedia Ii - Anti-diabetic Drug - Biguanides
Biguanides reduce hepatic glucose output. Although it must be used with caution in patients with impaired liver or kidney function, metfo...   » Read the article

Encyclopedia - Galega Officinalis: Encyclopedia Ii - Galega Officinalis - Medical Use
The Galega officinalis has been known since the Middle Ages for relieving the symptoms of diabetes mellitus. Upon analysis, it turned out...   » Read the article

Encyclopedia - Insulin Resistance: Encyclopedia Ii - Insulin Resistance - Therapy
Both metformin and the thiazolidinediones improve insulin resistance. Exercise, weight loss, and a low glycemic index diet may help. The ...   » Read the article

Encyclopedia - Insulin Resistance: Encyclopedia Ii - Insulin Resistance - Therapy
Both metformin and the thiazolidinediones improve insulin resistance. Exercise, weight loss, and a low glycemic index diet may help. The ...   » Read the article

Encyclopedia - Metabolic Acidosis: Encyclopedia Ii - Metabolic Acidosis - Causes
The causes are best grouped by their influence on the anion gap: Metabolic acidosis - Increased anion gap. lactic acidosis ketoacidosi...   » Read the article

Encyclopedia - Pharmacology: Encyclopedia - Pharmacology
Pharmacology (in Greek: pharmacon (φάρμακον) meaning drug, and logos (λόγος) meaning science) is the study of how chemical s...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia - Diabetes Mellitus
Diabetes mellitus is a medical disorder characterized by varying or persistent hyperglycemia (elevated blood sugar levels), especially af...   » Read the article

Encyclopedia - Obesity: Encyclopedia - Obesity
Obesity is a condition where the natural energy reserve, stored in the fatty tissue of humans and mammals is increased to the point where...   » Read the article

Encyclopedia - Pharmacology: Encyclopedia - Pharmacology
Pharmacology (in Greek: pharmacon (φάρμακον) meaning drug, and logos (λόγος) meaning science) is the study of how chemical s...   » Read the article

Encyclopedia - Obesity: Encyclopedia - Obesity
Obesity is a condition where the natural energy reserve, stored in the fatty tissue of humans and mammals is increased to the point where...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia - Diabetes Mellitus
Diabetes mellitus is a medical disorder characterized by varying or persistent hyperglycemia (elevated blood sugar levels), especially af...   » Read the article

Encyclopedia - Central Obesity: Encyclopedia - Central Obesity
Central obesity (or 'apple-shaped' or 'masculine' obesity) occurs when the main deposits of body fat are localised around the abdomen and...   » Read the article

Encyclopedia - Adverse Effect Medicine: Encyclopedia - Adverse Effect Medicine
Adverse effect, in medicine, is an abnormal, harmful, undesired and/or unintended consequences, although not necessarily unexpected, whic...   » Read the article

Encyclopedia - Diabetes Mellitus Type 2: Encyclopedia - Diabetes Mellitus Type 2
Diabetes mellitus type 2 (formerly called diabetes mellitus type II, non-insulin-dependent diabetes, NIDDM or adult-onset diabetes) is a ...   » Read the article

Encyclopedia - Folic Acid: Encyclopedia Ii - Folic Acid - What Are Some Current Issues And Controversies About Folate?
Folic acid - Dietary fortification of folic acid. Since the discovery of the link between insufficient folic acid and neural tube defec...   » Read the article

Encyclopedia - Insulin Resistance: Encyclopedia Ii - Insulin Resistance - Pathophysiology
In patients who use insulin, "insulin resistance" is production of antibodies against insulin that lead to lower-than-expected falls of g...   » Read the article

Encyclopedia - Polycystic Ovary Syndrome: Encyclopedia Ii - Polycystic Ovary Syndrome - Treatment
Medical treatment of PCOS used to be directed mainly at the symptoms (ovarian and adrenal suppression, and anti-androgen therapy) and res...   » Read the article

Encyclopedia - Diabetes Mellitus Type 2: Encyclopedia Ii - Diabetes Mellitus Type 2 - Pathophysiology
Genetic factors, usually polygenic, form disease background in a prevailing number of patients. Environmental factors like obesity, lack ...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Diagnosis
Diabetes mellitus - Signs and symptoms. Type 2 diabetes almost always has a slow onset (often years), but in type 1, particularly in ch...   » Read the article

Encyclopedia - Non-alcoholic Steatohepatitis: Encyclopedia Ii - Non-alcoholic Steatohepatitis - Signs And Symptoms
Sometimes dull right upper quadrant pain is felt, occasionally radiating to the right shoulder. Mild jaundice can sometimes be noticed. N...   » Read the article

Encyclopedia - Maturity Onset Diabetes Of The Young: Encyclopedia Ii - Maturity Onset Diabetes Of The Young - Signs Symptoms And Differential Diagnosis
There are two general types of clinical presentation. Some forms of MODY produce significant hyperglycemia and the typical signs and symp...   » Read the article

Encyclopedia - Pharmacology: Encyclopedia Ii - Pharmacology - Types Of Medication
Pharmacology - For the gastrointestinal tract or digestive system. Upper digestive tract: antacids, reflux suppressants, antiflatulent...   » Read the article

Encyclopedia - Adverse Effect Medicine: Encyclopedia Ii - Adverse Effect Medicine - Reporting Systems
In many countries, adverse effects are required by law to be reported, researched in clinical trials and included into the patient inform...   » Read the article

Encyclopedia - Hyperinsulinism: Encyclopedia Ii - Hyperinsulinism - Hyperinsulinism Due To Diminished Sensitivity Associated With Diabetes Risk
Although many factors influence insulin secretion, arguably the most important control is the level of glucose entering the beta cells of...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Diagnosis
Diabetes mellitus - Signs and symptoms. Type 2 diabetes almost always has a slow onset (often years), but in type 1, particularly in ch...   » Read the article

Encyclopedia - Obesity: Encyclopedia Ii - Obesity - Causes
Obesity - Causative factors. Obesity is believed to be caused by excessive caloric intake accompanied with insufficient caloric expendi...   » Read the article

Encyclopedia - Metabolic Syndrome: Encyclopedia Ii - Metabolic Syndrome - Nomenclature
Other names for this syndrome are: Syndrome X; Metabolic syndrome X; Insulin resistance syndrome; Reaven's Syndrome, after Dr Gerald M. ...   » Read the article

Encyclopedia - Central Obesity: Encyclopedia Ii - Central Obesity - Associations
Central obesity is common in polycystic ovary syndrome (PCOS) and Syndrome X, and it is associated with a statistically higher risk of he...   » Read the article

Encyclopedia - Metabolic Acidosis: Encyclopedia Ii - Metabolic Acidosis - Signs And Symptoms
Symptoms are aspecific, and diagnosis can be difficult unless the patient presents with clear indications for arterial blood gas sampling...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Diagnosis
Diabetes mellitus - Signs and symptoms. Type 2 diabetes almost always has a slow onset (often years), but in type 1, particularly in ch...   » Read the article

Encyclopedia - Obesity: Encyclopedia Ii - Obesity - Causes
Obesity - Causative factors. When energy intake exceeds energy expenditure, fat cells (and to a lesser extent muscle and liver cells) t...   » Read the article

Encyclopedia - Polycystic Ovary Syndrome: Encyclopedia Ii - Polycystic Ovary Syndrome - Pathogenesis
PCOS develops when the ovaries are stimulated to produce excessive amounts of male hormones (androgens), particularly testosterone - eith...   » Read the article

Encyclopedia - Non-alcoholic Steatohepatitis: Encyclopedia Ii - Non-alcoholic Steatohepatitis - Laboratory Imaging And Diagnosis
Disturbed liver enzymes are common. Other tests generally performed are other blood tests (erythrocyte sedimentation rate, glucose, album...   » Read the article

Encyclopedia - Polycystic Ovary Syndrome: Encyclopedia Ii - Polycystic Ovary Syndrome - Diagnosis
It is vital to note that not all women with PCOS have polycystic ovaries, nor do all women with ovarian cysts have PCOS; although a pelvi...   » Read the article

Encyclopedia - Non-alcoholic Steatohepatitis: Encyclopedia Ii - Non-alcoholic Steatohepatitis - Causes
The main cause is insulin resistance, which explains co-occurrence of NASH and syndrome X. NASH can also be caused by the following medic...   » Read the article

Encyclopedia - Polycystic Ovary Syndrome: Encyclopedia Ii - Polycystic Ovary Syndrome - Definition
There are two definitions that are commonly used: In 1990 a consensus workshop sponsored by the NIH/NICHD suggested that a patient has P...   » Read the article

Encyclopedia - Polycystic Ovary Syndrome: Encyclopedia Ii - Polycystic Ovary Syndrome - Signs And Symptoms
Common symptoms of PCOS include: Oligomenorrhea, amenorrhea - irregular/few, or absent, menstrual periods; cycles that do occur may comp...   » Read the article

Encyclopedia - Polycystic Ovary Syndrome: Encyclopedia Ii - Polycystic Ovary Syndrome - Risks
Women with PCOS are at risk for the following: Endometrial hyperplasia and endometrial cancer (cancer of the uterine lining) are possibl...   » Read the article

Encyclopedia - Obesity: Encyclopedia Ii - Obesity - Definition
Obesity is a concept that is being continually redefined. In humans, the most common statistical estimate of excess fat mass is the body ...   » Read the article

Encyclopedia - Obesity: Encyclopedia Ii - Obesity - Controversies
There is continuous debate over obesity, at several levels. While scientific evidence for particular risks and treatments is fairly firm,...   » Read the article

Encyclopedia - Obesity: Encyclopedia Ii - Obesity - Therapy
The mainstay of treatment for obesity is an energy-limited diet and increased exercise. In studies, diet and exercise programs have consi...   » Read the article

Encyclopedia - Obesity: Encyclopedia Ii - Obesity - Complications
Obesity, especially central obesity (male-type or waist-predomimant obesity), is an important risk factor for the "metabolic syndrome" ("...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - History
Although diabetes has been recognized since antiquity, and treatments were known since the Middle Ages, the elucidation of the pathogenes...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Long-term Complications
Among the major risks of the disorder are chronic problems affecting multiple organ systems which will eventually arise in patients with ...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Curing Diabetes
A disease consisting of the failure of a single organ (type 1 diabetes, the Islets of Langerhans) with a relatively simple function shoul...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Management Of The Disease
See also: Diabetes management Diabetes is a chronic disease with no cure (except experimentally in type 1 diabetics) as of 2005. Manageme...   » Read the article

Encyclopedia - Obesity: Encyclopedia Ii - Obesity - Cultural And Social Significance
Obesity - Culture and obesity. In several human cultures, obesity is associated with attractiveness, strength, and fertility. Some of t...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Etymology
The word diabetes was coined by Aretaeus (81–133 CE) of Cappadocia. The word is taken from Greek diabaínein, and literally means "pass...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Long-term Complications
Among the major risks of the disorder are chronic problems affecting multiple organ systems which will eventually arise in patients with ...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Causes And Types
Diabetes mellitus - The role of insulin. Since insulin is the principal hormone that regulates uptake of glucose into cells (primarily ...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Management Of The Disease
See also: Diabetes management Diabetes is a chronic disease with no cure (except experimentally in type 1 diabetics) as of 2005. Manageme...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Curing Diabetes
A disease consisting of the failure of a single organ (type 1 diabetes, the Islets of Langerhans) with a relatively simple function shoul...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Statistics
In 2004, according to the World Health Organization, more than 150 million people worldwide suffered from diabetes. Its incidence is incr...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Public Health Policy And Health Economics
The Declaration of St Vincent was the result of international efforts to improve the care accorded to diabetics. Doing so is important if...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - History
Although diabetes has been recognized since antiquity, and treatments were known since the Middle Ages, the elucidation of the pathogenes...   » Read the article

Encyclopedia - Maturity Onset Diabetes Of The Young: Encyclopedia Ii - Maturity Onset Diabetes Of The Young - Mody 1: Hepatocyte Nuclear Factor 4α
MODY 1 is due to a loss-of-function mutation in the HNF4α gene on chromosome 20 that codes for transcription factor 14 (TCF14). HNF4α c...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Management Of The Disease
See also: Diabetes management Diabetes is a chronic disease with no cure (except experimentally in type 1 diabetics) as of 2005. Manageme...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Long-term Complications
Among the major risks of the disorder are chronic problems affecting multiple organ systems which will eventually arise in patients with ...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Causes And Types
Diabetes mellitus - The role of insulin. Since insulin is the principal hormone that regulates uptake of glucose into cells (primarily ...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Curing Diabetes
A disease consisting of the failure of a single organ (type 1 diabetes, the Islets of Langerhans) with a relatively simple function shoul...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Public Health Policy And Health Economics
The Declaration of St Vincent was the result of international efforts to improve the care accorded to diabetics. Doing so is important if...   » Read the article

Encyclopedia - Pharmacology: Encyclopedia Ii - Pharmacology - Scientific Background
The study of medicinal chemicals requires intimate knowledge of the biological system affected. With the knowledge of cell biology and bi...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Etymology
"Diabetes" is a Greek word meaning "a passer through; a siphon". "Mellitus" comes from the Greek word "sweet". Apparently, the Greeks nam...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - Statistics
In 2004, according to the World Health Organization, more than 150 million people worldwide suffered from diabetes. Its incidence is incr...   » Read the article

Encyclopedia - Diabetes Mellitus: Encyclopedia Ii - Diabetes Mellitus - History
Although diabetes has been recognized since antiquity, and treatments were known since the Middle Ages, the elucidation of the pathogenes...   » Read the article

Encyclopedia - Adverse Effect Medicine: Encyclopedia Ii - Adverse Effect Medicine - Controversies
Sometimes, putative medical adverse effects are regarded as controversial and generate heated discussions in society and lawsuits against...   » Read the article

Encyclopedia - Obesity: Encyclopedia Ii - Obesity - Complications
Obesity, especially central obesity (male-type or waist-predomimant obesity), is an important risk factor for the "metabolic syndrome" ("...   » Read the article

Encyclopedia - Obesity: Encyclopedia Ii - Obesity - Cultural And Social Significance
Obesity - Culture and obesity. In several human cultures, obesity is associated with attractiveness, strength, and fertility. Some of t...   » Read the article

Encyclopedia - Obesity: Encyclopedia Ii - Obesity - Definition
Obesity is a concept that is being continually redefined. In humans, the most common statistical estimate of obesity is the body mass ind...   » Read the article

Encyclopedia - Obesity: Encyclopedia Ii - Obesity - Therapy
The mainstay of treatment for obesity is an energy-limited diet and increased exercise. Although adherence to this regimen can cure obesi...   » Read the article

Encyclopedia - Obesity: Encyclopedia Ii - Obesity - Controversies
There is continuous debate over obesity, at several levels. While scientific evidence for particular risks and treatments is fairly firm,...   » Read the article

Encyclopedia - Adverse Effect Medicine: Encyclopedia Ii - Adverse Effect Medicine - Adverse Effects Of Drugs
Adverse effects can occur as a collateral or side effect of many interventions, but they are particularly important in pharmacology, due ...   » Read the article

Encyclopedia - Adverse Effect Medicine: Encyclopedia Ii - Adverse Effect Medicine - Adverse Effects Of Medical Procedures
Surgery, of course, may have a number of undesirable or harmful after effects, such as infection, hemorrhage, inflammation, scarring, los...   » Read the article

Encyclopedia - Diabetes Mellitus Type 2: Encyclopedia Ii - Diabetes Mellitus Type 2 - Treatment
Diabetes mellitus type 2 is a chronic, progressive disease that cannot be cured. It implicates two main goals of treatment of the disease...   » Read the article

Encyclopedia - Folic Acid: Encyclopedia Ii - Folic Acid - Biochemistry
In the form of a series of tetrahydrofolate compounds, folate derivatives are coenzymes in a number of single carbon transfer reactions b...   » Read the article

Encyclopedia - Maturity Onset Diabetes Of The Young: Encyclopedia Ii - Maturity Onset Diabetes Of The Young - Complications And Goals Of Management
Unfortunately, chronic hyperglycemia of any cause can eventually cause blood vessel damage and the microvascular complications of diabete...   » Read the article

Encyclopedia - Maturity Onset Diabetes Of The Young: Encyclopedia Ii - Maturity Onset Diabetes Of The Young - Mody X: Other Possible Forms Of Mody
The known 6 types described above account for about 85-90% of cases identified by clinical criteria, suggesting that there are other form...   » Read the article

Encyclopedia - Maturity Onset Diabetes Of The Young: Encyclopedia Ii - Maturity Onset Diabetes Of The Young - Mody 6: Neurogenic Differentiation 1
MODY 6 arises from mutations of the gene for the transcription factor referred to as neurogenic differentiation 1. The gene is on chromos...   » Read the article

Encyclopedia - Maturity Onset Diabetes Of The Young: Encyclopedia Ii - Maturity Onset Diabetes Of The Young - Related Homozygous Disorders
By definition, the forms of MODY are autosomal dominant, requiring only one abnormal gene to produce the disease; the severity of the dis...   » Read the article

Encyclopedia - Metabolic Acidosis: Encyclopedia Ii - Metabolic Acidosis - Diagnosis
Arterial blood gas sampling is essential for the diagnosis. The pH is low (under 7.35) and the bicarbonate levels are decreased (<12 m...   » Read the article

Encyclopedia - Metabolic Syndrome: Encyclopedia Ii - Metabolic Syndrome - Signs And Symptoms
Symptoms and features are: Diabetes mellitus type II (or impaired glucose tolerance or insulin resistance); High blood pressure; Central...   » Read the article

Encyclopedia - Metabolic Acidosis: Encyclopedia Ii - Metabolic Acidosis - Pathophysiology
Metabolic acidosis - Compensatory mechanisms. Metabolic acidosis is either due to increased generation of acid or an inability to gener...   » Read the article

Encyclopedia - Maturity Onset Diabetes Of The Young: Encyclopedia Ii - Maturity Onset Diabetes Of The Young - Mody 5: Hepatocyte Nuclear Factor 1β
HNF1β-related MODY is one of the less common forms of MODY, with some distinctive clinical features, including atrophy of the pancreas a...   » Read the article

Encyclopedia - Maturity Onset Diabetes Of The Young: Encyclopedia Ii - Maturity Onset Diabetes Of The Young - Mody 4: Insulin Promoter Factor-1
MODY 4 arises from mutations of the IPF1 homeobox gene on chromosome 13. IPF1 is a transcription factor vital to the development of the e...   » Read the article

Encyclopedia - Folic Acid: Encyclopedia Ii - Folic Acid - Folic Acid Supplements And Masking Of B12 Deficiency
There has been concern about the interaction between vitamin B12 and folic acid. Folic acid supplements can correct the anemia associated...   » Read the article

Encyclopedia - Folic Acid: Encyclopedia Ii - Folic Acid - Folate Deficiency
Signs of folic acid deficiency are often subtle. Diarrhea, loss of appetite, and weight loss can occur. Additional signs are weakness, so...   » Read the article

Encyclopedia - Folic Acid: Encyclopedia Ii - Folic Acid - Recommended Dietary Allowance For Folate
The Recommended Dietary Allowance (RDA) is the average daily dietary intake level that is sufficient to meet the nutrient requirements of...   » Read the article

Encyclopedia - Insulin Resistance: Encyclopedia Ii - Insulin Resistance - Investigation
Insulin resistance - Glucose tolerance testing GTT. During a glucose tolerance test (GTT), which is generally used to diagnose diabetes...   » Read the article

Encyclopedia - Maturity Onset Diabetes Of The Young: Encyclopedia Ii - Maturity Onset Diabetes Of The Young - History Of The Concept And Treatment Of Mody
The term MODY dates back to 1964, when diabetes mellitus was considered to have two main forms: juvenile-onset and maturity-onset, which ...   » Read the article

Encyclopedia - Maturity Onset Diabetes Of The Young: Encyclopedia Ii - Maturity Onset Diabetes Of The Young - Mody 3: Hepatocyte Nuclear Factor 1α
MODY 3 is caused by mutations of the HNF1α gene, a homeobox gene on chromosome 12. This is the most common type of MODY in populations w...   » Read the article

Encyclopedia - Maturity Onset Diabetes Of The Young: Encyclopedia Ii - Maturity Onset Diabetes Of The Young - Mody 2: Glucokinase
MODY 2 is due to any of several mutations in the GCK gene on chromosome 7 for glucokinase. Glucokinase serves as the glucose sensor for t...   » Read the article

Encyclopedia - Metabolic Syndrome: Encyclopedia Ii - Metabolic Syndrome - History
The Marseilles physician Dr Jean Vague appears to have been one of the first to link abdominal obesity with metabolic abnormalities in 19...   » Read the article