Daily doses vary greatly from 0.5 mg bedtime for insomnia and 2.5 mg every 6 hours and more in the acute treatment of mania, before the firstline drugs (lithium, valproic acid) control the situation. Catatonia with inability to speak is very responsive and sometimes controlled with a single dose of 2 mg oral or slow i.v. injection. Catatonia may reoccur and treatment for some days may be necessary. Sometimes haloperidol is given concomitantly. The control of status epilepticus requires slow i.v. injections of 2 to 4 (or even 8) mg. Patients should be closely monitored for respiratory ...

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Lorazepam, Lorazepam - Indications, Lorazepam - Pharmacological Data and Pharmacokinetics, Lorazepam - Dosage, Lorazepam - Disadvantages, Lorazepam - Abuse, Lorazepam - Legal issues

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Lorazepam, Lorazepam - Indications, Lorazepam - Pharmacological Data and Pharmacokinetics, Lorazepam - Dosage, Lorazepam - Disadvantages, Lorazepam - Abuse, Lorazepam - Legal issues

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Lorazepam is rapidly and nearly completely absorbed after any mode of application (oral, sublingual, i.m., i.v.). After i.v.-injection onset of action is within minutes and may be delayed to 30-45 minutes after oral/sublingual dose and up to 1 hour after i.m. use. The duration of action depends on the dose and is normally 6 to 12 hours. The half-life of lorazepam in patients with normal liver function is 11 to 18 hours. Therefore, 2-4 daily doses are often needed. A dose equivalent to 5 mg of diazepam is 500 micrograms (0.5 mg) of lorazepam. [1]. Other experts estim ...

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Lorazepam is a benzodiazepine used to treat anxiety disorders and insomnia, as well as certain types of seizures. It is sold under the brand names Ativan®, Temesta®, Tavor® (in Europe) and as generic lorazepam. It is available in tablets and as a solution for intramuscular and intravenous injections. Its formula is C15H10Cl2N2O2 and its CAS number is 846-49-1. Pharmacologically it is classified as a sedative-hypnotic, anxiolytic and anticonvulsant.Including:

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Trimipramine is not an abusable substance nor does it cause psychological dependence. Withdrawal symptoms frequently seen when treatment with Trimipramine is stopped abruptly (agitation, anxiety, insomnia, sometimes activation of mania or rebound depression) are not indicative of addiction and can be avoided by reducing the daily dose of Trimipramine gradually by approximately 25% each week. If treatment has to be stopped at once due to medical reasons, the use of a benzodiazepine (e.g. Lorazepam, Clonazepam, or Alprazolam) for a maximum of 4 ...

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Trimipramine, Trimipramine - Pharmacology, Trimipramine - Metabolism, Trimipramine - Indications, Trimipramine - Contraindications, Trimipramine - Side Effects, Trimipramine - Interactions, Trimipramine - Drug Abuse and Dependence, Trimipramine - Necessary Examinations during Treatment, Trimipramine - Dosage, Trimipramine - Parenteral Usage, Trimipramine - Usual Dosage Forms, Trimipramine - Brands, Trimipramine - References and End Notes

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Maprotiline has no potential for abuse and psychological dependence. Withdrawal symptoms frequently seen when treatment with Maprotiline is stopped abruptly (agitation, anxiety, insomnia, sometimes activation of mania or rebound depression) are not indicative of addiction and can be avoided by reducing the daily dose of Maprotiline gradually by approximately 25% each week. If treatment has to be stopped at once due to medical reasons, the use of a benzodiazepine (e.g. Lorazepam, Clonazepam, or Alprazolam) for a maximum of 4 w ...

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