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Chagas disease - History | A Wisdom Archive on Chagas disease - History | | Chagas disease - History A selection of articles related to Chagas disease - History | |
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Chagas disease, Chagas disease - Alternative infection mechanism, Chagas disease - Clinical manifestations, Chagas disease - Epidemiology and geographical distribution, Chagas disease - History, Chagas disease - Infection cycle, Chagas disease - Laboratory diagnosis, Chagas disease - Original publication, Chagas disease - Prevention, Chagas disease - Sources, Chagas disease - Treatment, Tropical disease, In Jalisco, Huichol -Indians used to eat reduviid bugs in hot sauce. In other mexican communities there is a believe, that the bugs feces can cure warts or that the bugs have aphrodisiac powers.
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ARTICLES RELATED TO Chagas disease - History | | | |  Chagas disease - History: Encyclopedia II - Chagas disease - HistoryThe disease was named after the Brazilian physician and infectologist Carlos Chagas, who first described it in 1909, but the disease was not seen as a major public health problem in humans until the 1960s. He discovered that the intestines of Triatomidae harbored a flagellate protozoan, a new species of the Trypanosoma genus, and was able to prove experimentally that it could be transmitted to marmoset monk ...
See also:Chagas disease, Chagas disease - History, Chagas disease - Epidemiology and geographical distribution, Chagas disease - Clinical manifestations, Chagas disease - Infection cycle, Chagas disease - Alternative infection mechanism, Chagas disease - Laboratory diagnosis, Chagas disease - Treatment, Chagas disease - Prevention, Chagas disease - Original publication, Chagas disease - Sources Read more here: » Chagas disease: Encyclopedia II - Chagas disease - History |
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| | | | Chagas disease - History: Encyclopedia II - Chagas disease - Prevention A reasonably effective vaccine was developed in Ribeirão Preto in the 1970s, using cellular and subcellular fractions of the parasite, but it was found economically unfeasible. More recently, the potential of DNA vaccines for immunotherapy of acute and chronic Chagas disease is being tested by several research groups.
Prevention is centered on fighting the vector (Triatoma) by using sprays and paints containing insecticides (synthetic pyrethroids), and improving housing and sanitary conditions in the rural area. For urban dwel ...
See also:Chagas disease, Chagas disease - History, Chagas disease - Epidemiology and geographical distribution, Chagas disease - Clinical manifestations, Chagas disease - Infection cycle, Chagas disease - Alternative infection mechanism, Chagas disease - Laboratory diagnosis, Chagas disease - Treatment, Chagas disease - Prevention, Chagas disease - Original publication, Chagas disease - Sources Read more here: » Chagas disease: Encyclopedia II - Chagas disease - Prevention |
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| | | | Chagas disease - History: Encyclopedia II - Chagas disease - Treatment Medication for Chagas disease is usually only effective when given during the acute stage of infection. The drugs of choice are azole or nitroderivatives such as benznidazole [8] or nifurtimox (under an Investigational New Drug protocol from the CDC Drug Service), but resistance to these drugs has already been reported [9]. Furthermore, these agents are very toxic and have many adverse effects, and cannot be taken without medical supervision. A 10-year study of chronic administration of drugs in Brazil has revealed that these drugs are not t ...
See also:Chagas disease, Chagas disease - History, Chagas disease - Epidemiology and geographical distribution, Chagas disease - Clinical manifestations, Chagas disease - Infection cycle, Chagas disease - Alternative infection mechanism, Chagas disease - Laboratory diagnosis, Chagas disease - Treatment, Chagas disease - Prevention, Chagas disease - Original publication, Chagas disease - Sources Read more here: » Chagas disease: Encyclopedia II - Chagas disease - Treatment |
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| | | | Chagas disease - History: Encyclopedia II - Chagas disease - Clinical manifestations The human disease occurs in two stages: the acute stage shortly after the infection. A local lesion (so called chagoma (see picture), palpebral edema) can appear at the site of inoculation. The acute phase is usually asymptomatic, but can present with manifestations that include fever, anorexia, lymphadenopathy, mild hepatosplenomegaly, and myocarditis. Some acute cases (10 to 20%) resolve over a period of 2 to 3 months into an asympto ...
See also:Chagas disease, Chagas disease - History, Chagas disease - Epidemiology and geographical distribution, Chagas disease - Clinical manifestations, Chagas disease - Infection cycle, Chagas disease - Alternative infection mechanism, Chagas disease - Laboratory diagnosis, Chagas disease - Treatment, Chagas disease - Prevention, Chagas disease - Original publication, Chagas disease - Sources Read more here: » Chagas disease: Encyclopedia II - Chagas disease - Clinical manifestations |
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| | | | Chagas disease - History: Encyclopedia II - Chagas disease - Epidemiology and geographical distribution Chagas disease currently affects 16-18 million people, killing around 20,000 people annually and with some 100 million at risk of acquiring the disease. Chronic Chagas disease remains a major health problem in many Latin American countries, despite the effectiveness of hygienic and preventive measures, such as eliminating the transmitting insects, which have reduced to zero new infections in at least two countries of the region. With increased population movements, however, the possibility of transmission by blood transfusion has become more ...
See also:Chagas disease, Chagas disease - History, Chagas disease - Epidemiology and geographical distribution, Chagas disease - Clinical manifestations, Chagas disease - Infection cycle, Chagas disease - Alternative infection mechanism, Chagas disease - Laboratory diagnosis, Chagas disease - Treatment, Chagas disease - Prevention, Chagas disease - Original publication, Chagas disease - Sources Read more here: » Chagas disease: Encyclopedia II - Chagas disease - Epidemiology and geographical distribution |
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| | | | Chagas disease - History: Encyclopedia II - Chagas disease - Infection cycle An infected triatomine insect vector takes a blood meal and releases trypomastigotes in its feces near the site of the bite wound. By scratching the site of the bite, the victim allows trypomastigotes to enter the host through the wound, or through intact mucosal membranes, such as the conjunctiva. Inside the host, the trypomastigotes invade cells, where they differentiate into intracellular amastigotes. The amastigotes multiply by binary fission and differentiate into trypomastigotes, and then are released into the circulation as bloodstrea ...
See also:Chagas disease, Chagas disease - History, Chagas disease - Epidemiology and geographical distribution, Chagas disease - Clinical manifestations, Chagas disease - Infection cycle, Chagas disease - Alternative infection mechanism, Chagas disease - Laboratory diagnosis, Chagas disease - Treatment, Chagas disease - Prevention, Chagas disease - Original publication, Chagas disease - Sources Read more here: » Chagas disease: Encyclopedia II - Chagas disease - Infection cycle |
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