Encyclopedia - Zidovudine: Encyclopedia - Zidovudine
AZT 3'-Azido-2'-deoxythymidine Zidovudine (INN) or azidothymidine (abbreviated to AZT) is an antiretroviral drug, the first antiviral tr...   » Read the article

Encyclopedia - Cyclophosphamide: Encyclopedia - Cyclophosphamide
Cyclophosphamide Cyclophosphamide is a nitrogen mustard alkylating agent, used to treat various types of cancer and some autoimmune diso...   » Read the article

Encyclopedia - Brca2: Encyclopedia - Brca2
BRCA2 is a human gene that is involved in the repair of chromosomal damage and belongs to a class of genes known as tumor suppressor gene...   » Read the article

Encyclopedia - Azathioprine: Encyclopedia - Azathioprine
Azathioprine is a chemotherapy drug, now rarely used for chemotherapy but more for immunosuppression in organ transplantation and autoimm...   » Read the article

Encyclopedia - Zidovudine: Encyclopedia Ii - Zidovudine - History
Zidovudine was the first drug approved for the treatment of AIDS and HIV infection. Jerome Horowitz first synthesized AZT in 1964, under ...   » Read the article

Encyclopedia - Cyclophosphamide: Encyclopedia Ii - Cyclophosphamide - Uses
The main use of cyclophosphamide is together with other chemotherapy agents in the treatment of lymphomas, some forms of leukemia and som...   » Read the article

Encyclopedia - Zidovudine: Encyclopedia Ii - Zidovudine - History
Zidovudine was the first drug approved for the treatment of AIDS and HIV infection. Jerome Horowitz first synthesized AZT in 1964, under ...   » Read the article

Encyclopedia - Brca2: Encyclopedia Ii - Brca2 - Related Conditions
Certain variations of the BRCA2 gene cause an increased risk for breast cancer. Researchers have identified about 450 mutations in the BR...   » Read the article

Encyclopedia - Cyclophosphamide: Encyclopedia Ii - Cyclophosphamide - Side-effects
Side-effects include chemotherapy-induced nausea and vomiting (CINV), bone marrow suppression, alopecia (hair loss) and lethargy. Hemorrh...   » Read the article

Encyclopedia - Cyclophosphamide: Encyclopedia Ii - Cyclophosphamide - Mode Of Action
The main effect of cyclophosphamide is due to its metabolite phosphoramide mustard. This metabolite is only formed in cells which have lo...   » Read the article