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biochemical cascade

A Wisdom Archive on biochemical cascade

biochemical cascade

A selection of articles related to biochemical cascade

More material related to Biochemical Cascade can be found here:
Index of Articles
related to
Biochemical Cascade
biochemical cascade

ARTICLES RELATED TO biochemical cascade

biochemical cascade: Encyclopedia - Traumatic brain injury

Traumatic brain injury (TBI), traumatic injuries to the brain, also called acquired brain injury, intracranial injury, or simply head injury, occurs when a sudden trauma causes damage to the brain. Parts of the brain that can be damaged include the cerebral hemispheres, cerebellum, and brain stem (see brain damage). Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. Outcome can be anything from complete recovery to permanent disability or death. Traumatic brain injury ...

Including:

Read more here: » Traumatic brain injury: Encyclopedia - Traumatic brain injury

biochemical cascade: Encyclopedia - Stroke

A stroke or cerebrovascular accident (CVA) occurs when the blood supply to a part of the brain is suddenly interrupted. In brain tissue, a reduction of blood flow, ischemia, leads to an ischemic cascade that can damage or kill brain cells. Death of brain tissue can lead to loss of the function controlled by that tissue. Thus stroke is the third leading cause of death and leading cause of adult disability in the US and industrialized European nations (Jauch, 2005), and is a medical emergency. To underscore the seriousness ...

Including:

Read more here: » Stroke: Encyclopedia - Stroke

biochemical cascade: Encyclopedia - Complement system

The complement system is derived from many small plasma proteins that form the complex biochemical cascade of the immune system, leading to cytolysis, chemotaxis, opsonization and inflammation, it can mark pathogens for phagocytosis. It consists of more than 35 proteins. 12 which are directly involved in the complement pathways, while the rest have regulatory functions. There are three biochemical pathways which activates the complement system: the classical complement pathway, the alternate complement pathway and the mannan-binding l ...

Including:

Read more here: » Complement system: Encyclopedia - Complement system

biochemical cascade: Encyclopedia II - Penetrating head injury - Mechanisms

In penetrating injury from high velocity missiles, injuries may occur not only from initial laceration and crushing of brain tissue by the projectile but also from the subsequent cavitation. High velocity objects create centrifugal forces and can create a shock wave that cause stretch injuries, forming a cavity that is three to four times greater in diameter than the missile itself (Vinas and Pilistis, 2004). A pulsating temporary cavity is also formed by a high-speed missile and can have a diameter thirty times greater than that of the miss ...

See also:

Penetrating head injury, Penetrating head injury - Mechanisms, Penetrating head injury - Pathophysiology, Penetrating head injury - Outcome

Read more here: » Penetrating head injury: Encyclopedia II - Penetrating head injury - Mechanisms

biochemical cascade: Encyclopedia II - Subdural hematoma - Signs and symptoms

Symptoms of subdural hemorrhage have a slower onset than those of epidural hemorrhages because the lower pressure veins bleed more slowly than arteries. Thus, signs and symptoms may show up within 24 hours but can be delayed as much as 2 weeks (Sanders and McKenna, 2001). If the bleeds are large enough to put pressure on the brain, signs of increased ICP or damage to part of the brain will be present (Wagner, 2004). Other signs and symptoms of subdural hematoma include the following: A history of recent head injury < ...

See also:

Subdural hematoma, Subdural hematoma - Causes, Subdural hematoma - Signs and symptoms, Subdural hematoma - Features, Subdural hematoma - Subtypes, Subdural hematoma - Pathophysiology, Subdural hematoma - Treatment, Subdural hematoma - Risk factors, Subdural hematoma - Prevention

Read more here: » Subdural hematoma: Encyclopedia II - Subdural hematoma - Signs and symptoms

biochemical cascade: Encyclopedia II - Complement system - Outline

The three pathways all generate homologous variants of the protease, C3-convertase. C3-convertase cleaves and activates C3, creating C3a and C3b and causing a cascade of further cleavage and activation events. C3b binds to the surface of pathogens leading to greater internalization by phagocytic cells. C5a is an important chemokine, which leads to the recruitment of inflammatory cells. C5b is initiates the membrane attack pathway which results in the membrane attack complex (MAC), consisting of C5b, C6, C7, C8, and polymeric C9. MAC is the cytolytic endproduct of the complement cascade, it forms a transmembrane channel w ...

See also:

Complement system, Complement system - Outline, Complement system - Classical pathway, Complement system - Alternative pathway, Complement system - Lectin pathway, Complement system - Role in disease

Read more here: » Complement system: Encyclopedia II - Complement system - Outline

biochemical cascade: Encyclopedia II - Stroke - Treatment

Stroke - Early assessment. It is important to identify a stroke as early as possible because patients who are treated earlier are more likely to survive and have better recoveries. If a patient is suspected of having a stroke, emergency services should be contacted immediately. The patient should be transported to the nearest hospital that can provide a rapid evaluation and treatment with the latest available therapies targeted to the type of stroke. The faster these therapies are started for hemorrhagic a ...

See also:

Stroke, Stroke - Types of stroke, Stroke - Ischemic stroke, Stroke - Hemorrhagic stroke, Stroke - Watershed stroke, Stroke - Rarer types of stroke, Stroke - Causes, Stroke - Ischemic stroke, Stroke - Hemorrhagic stroke, Stroke - Watershed stroke, Stroke - Signs and symptoms, Stroke - Diagnosis, Stroke - Pathophysiology, Stroke - Prevention, Stroke - Treatment, Stroke - Early assessment, Stroke - Ischemic stroke, Stroke - Hemorrhagic stroke, Stroke - Care and rehabilitation, Stroke - Prognosis, Stroke - Risk factors, Stroke - History

Read more here: » Stroke: Encyclopedia II - Stroke - Treatment

biochemical cascade: Encyclopedia II - Traumatic brain injury - Complications

Sometimes, health complications occur in the period immediately following a TBI. These complications are not types of TBI, but are distinct medical problems that arise as a result of the injury. Although complications are rare, the risk increases with the severity of the trauma. Complications of TBI include immediate seizures, hydrocephalus or post-traumatic ventricular enlargement, cerebrospinal fluid leaks, infections, vascular injuries, cranial nerve injuries, pain, bed sores, multiple organ system failure in unconscious patients, and polytrauma (trau ...

See also:

Traumatic brain injury, Traumatic brain injury - Epidemiology, Traumatic brain injury - Signs and Symptoms of TBI, Traumatic brain injury - Causes of and Risk Factors for TBI, Traumatic brain injury - Types of TBI, Traumatic brain injury - Effects on consciousness, Traumatic brain injury - Complications, Traumatic brain injury - General Trauma, Traumatic brain injury - Disabilities Resulting From TBI, Traumatic brain injury - Other Long-Term Problems Associated With TBI, Traumatic brain injury - Treatment, Traumatic brain injury - Rehabilitation, Traumatic brain injury - Prevention, Traumatic brain injury - Famous persons with TBI

Read more here: » Traumatic brain injury: Encyclopedia II - Traumatic brain injury - Complications

biochemical cascade: Encyclopedia II - Subdural hematoma - Features

Most of the time, subdural hematomas occur around the tops and sides of the frontal and parietal lobes (University of Vermont; Wagner, 2004). They also occur in the posterior fossa, and near the falx cerebri and tentorium (Wagner, 2004). Unlike epidural hematomas, which cannot expand past the sutures of the skull, subdural hematomas can expand along the inside of the skull, creating a convex shape that follows the curve of the brain, stopping only at the dural re ...

See also:

Subdural hematoma, Subdural hematoma - Causes, Subdural hematoma - Signs and symptoms, Subdural hematoma - Features, Subdural hematoma - Subtypes, Subdural hematoma - Pathophysiology, Subdural hematoma - Treatment, Subdural hematoma - Risk factors, Subdural hematoma - Prevention

Read more here: » Subdural hematoma: Encyclopedia II - Subdural hematoma - Features

biochemical cascade: Encyclopedia II - Subdural hematoma - Subtypes

Subdural hematomas are divided into acute, subacute, and chronic, depending on their speed of onset. Acute subdural hematomas that are due to trauma are the most lethal of all head injuries and have a high mortality rate if they are not rapidly treated with surgical decompression. Acute bleeds develop after high speed acceleration or deceleration injuries and are increasingly severe with larger hematomas. They are most severe if associated with cerebral contusions (Wagner, 2004). Though much faster than chronic subdural bleeds, acute ...

See also:

Subdural hematoma, Subdural hematoma - Causes, Subdural hematoma - Signs and symptoms, Subdural hematoma - Features, Subdural hematoma - Subtypes, Subdural hematoma - Pathophysiology, Subdural hematoma - Treatment, Subdural hematoma - Risk factors, Subdural hematoma - Prevention

Read more here: » Subdural hematoma: Encyclopedia II - Subdural hematoma - Subtypes

biochemical cascade: Encyclopedia II - Traumatic brain injury - Causes of and Risk Factors for TBI

Half of all TBIs are due to transportation accidents involving automobiles, motorcycles, bicycles, and pedestrians. These accidents are the major cause of TBI in people under age 75. For those 75 and older, falls cause the majority of TBIs. Approximately 20 percent of TBIs are due to violence, such as firearm assaults and child abuse, and about 3 percent are due to sports injuries. Fully half of TBI incidents involve alcohol use. ...

See also:

Traumatic brain injury, Traumatic brain injury - Epidemiology, Traumatic brain injury - Signs and Symptoms of TBI, Traumatic brain injury - Causes of and Risk Factors for TBI, Traumatic brain injury - Types of TBI, Traumatic brain injury - Effects on consciousness, Traumatic brain injury - Complications, Traumatic brain injury - General Trauma, Traumatic brain injury - Disabilities Resulting From TBI, Traumatic brain injury - Other Long-Term Problems Associated With TBI, Traumatic brain injury - Treatment, Traumatic brain injury - Rehabilitation, Traumatic brain injury - Prevention, Traumatic brain injury - Famous persons with TBI

Read more here: » Traumatic brain injury: Encyclopedia II - Traumatic brain injury - Causes of and Risk Factors for TBI

biochemical cascade: Encyclopedia II - Traumatic brain injury - Types of TBI

The damage from TBI can be focal, confined to one area of the brain, or diffuse, involving more than one area of the brain. Diffuse trauma to the brain is frequently associated with concussion (a shaking of the brain in response to sudden motion of the head), diffuse axonal injury, or coma. Localized injuries may be associated with neurobehavioral manifestations, hemiparesis or other focal neurologic deficits. Types of focal brain injury include bruising of brain tissue called a contusion and intracranial hemorrhage or hematoma, heavy ...

See also:

Traumatic brain injury, Traumatic brain injury - Epidemiology, Traumatic brain injury - Signs and Symptoms of TBI, Traumatic brain injury - Causes of and Risk Factors for TBI, Traumatic brain injury - Types of TBI, Traumatic brain injury - Effects on consciousness, Traumatic brain injury - Complications, Traumatic brain injury - General Trauma, Traumatic brain injury - Disabilities Resulting From TBI, Traumatic brain injury - Other Long-Term Problems Associated With TBI, Traumatic brain injury - Treatment, Traumatic brain injury - Rehabilitation, Traumatic brain injury - Prevention, Traumatic brain injury - Famous persons with TBI

Read more here: » Traumatic brain injury: Encyclopedia II - Traumatic brain injury - Types of TBI

biochemical cascade: Encyclopedia II - Traumatic brain injury - Effects on consciousness

Generally, there are five abnormal states of consciousness that can result from a TBI: stupor, coma, persistent vegetative state, locked-in syndrome, and brain death. Stupor is a state in which the patient is unresponsive but can be aroused briefly by a strong stimulus, such as sharp pain. Coma is a state in which the patient is totally unconscious, unresponsive, unaware, and unarousable. Patients in a persistent vegetative state are unconscious and unaware of their surroundings, but they continue to have a sleep-wake cycle and ...

See also:

Traumatic brain injury, Traumatic brain injury - Epidemiology, Traumatic brain injury - Signs and Symptoms of TBI, Traumatic brain injury - Causes of and Risk Factors for TBI, Traumatic brain injury - Types of TBI, Traumatic brain injury - Effects on consciousness, Traumatic brain injury - Complications, Traumatic brain injury - General Trauma, Traumatic brain injury - Disabilities Resulting From TBI, Traumatic brain injury - Other Long-Term Problems Associated With TBI, Traumatic brain injury - Treatment, Traumatic brain injury - Rehabilitation, Traumatic brain injury - Prevention, Traumatic brain injury - Famous persons with TBI

Read more here: » Traumatic brain injury: Encyclopedia II - Traumatic brain injury - Effects on consciousness

biochemical cascade: Encyclopedia II - Subdural hematoma - Pathophysiology

Collected blood from the subdural bleed may draw in water due to osmosis, causing it to expand, which may compress brain tissue and cause new bleeds by tearing other blood vessels (Downie, 2001). The collected blood may even develop its own membrane (McCaffrey, 2001). In some subdural bleeds, the arachnoid layer of the meninges is torn, and cerebrospinal fluid (CSF) and blood both expand in the intracrania ...

See also:

Subdural hematoma, Subdural hematoma - Causes, Subdural hematoma - Signs and symptoms, Subdural hematoma - Features, Subdural hematoma - Subtypes, Subdural hematoma - Pathophysiology, Subdural hematoma - Treatment, Subdural hematoma - Risk factors, Subdural hematoma - Prevention

Read more here: » Subdural hematoma: Encyclopedia II - Subdural hematoma - Pathophysiology

biochemical cascade: Encyclopedia II - Subdural hematoma - Treatment

It is important that a patient receive medical assessment, including a complete neurological examination, after any head trauma. A CT scan or MRI scan will usually detect significant subdural hematomas. Treatment of a subdural hematoma depends on its size and rate of growth. Small subdural hematomas can be managed by careful monitoring until the body heals itself. Large or symptomatic hematomas require a craniotomy, the surgical opening of the skull. A surgeon then opens the dura, removes the blood clot with suction or irrigation, and ...

See also:

Subdural hematoma, Subdural hematoma - Causes, Subdural hematoma - Signs and symptoms, Subdural hematoma - Features, Subdural hematoma - Subtypes, Subdural hematoma - Pathophysiology, Subdural hematoma - Treatment, Subdural hematoma - Risk factors, Subdural hematoma - Prevention

Read more here: » Subdural hematoma: Encyclopedia II - Subdural hematoma - Treatment

biochemical cascade: Encyclopedia II - Penetrating head injury - Pathophysiology

Though it is more likely to cause infection, penetrating trauma is similar to closed head injury such as cerebral contusion or intracranial hemorrhage in a number of ways. As in closed head injury, intracranial pressure is likely to increase due to swelling or bleeding, potentially crushing delicate brain tissue. Most deaths from penetrating trauma are caused by damage to blood vessels, which can lead to intracranial hematomas and ischemia, which can in turn lead to a biochemical cascade called the ischemic cascade. Diffuse injury such as di ...

See also:

Penetrating head injury, Penetrating head injury - Mechanisms, Penetrating head injury - Pathophysiology, Penetrating head injury - Outcome

Read more here: » Penetrating head injury: Encyclopedia II - Penetrating head injury - Pathophysiology

biochemical cascade: Encyclopedia II - Penetrating head injury - Outcome

The highest velocity injuries tend to have the worst associated damage (Dawodu, 2004). Penetrating injury from any missile such as a bullet has a mortality rate of 92% (Vinas and Pilistis, 2004). Thus, firearms cause the most head injury-related deaths (BIAUSA). Injuries in which the projectile exits the other side are called perforating injuries, and these have an even worse prognosis (Vinas and Pilistis, 2004). Penetrating head trauma can cause loss of abilities controlled by parts of the brain that are damaged. A famous case of pen ...

See also:

Penetrating head injury, Penetrating head injury - Mechanisms, Penetrating head injury - Pathophysiology, Penetrating head injury - Outcome

Read more here: » Penetrating head injury: Encyclopedia II - Penetrating head injury - Outcome

biochemical cascade: Encyclopedia II - Traumatic brain injury - Signs and Symptoms of TBI

Some symptoms are evident immediately, while others do not surface until several days or weeks after the injury. With mild TBI, the patient may remain conscious or may lose consciousness for a few seconds or minutes. The person may also feel dazed or not like him- or herself for several days or weeks after the initial injury. Other symptoms include: headache, mental confusion, lightheadedness, dizziness, double vision, blurred vision, or tired eyes, ringing in the ears,< ...

See also:

Traumatic brain injury, Traumatic brain injury - Epidemiology, Traumatic brain injury - Signs and Symptoms of TBI, Traumatic brain injury - Causes of and Risk Factors for TBI, Traumatic brain injury - Types of TBI, Traumatic brain injury - Effects on consciousness, Traumatic brain injury - Complications, Traumatic brain injury - General Trauma, Traumatic brain injury - Disabilities Resulting From TBI, Traumatic brain injury - Other Long-Term Problems Associated With TBI, Traumatic brain injury - Treatment, Traumatic brain injury - Rehabilitation, Traumatic brain injury - Prevention, Traumatic brain injury - Famous persons with TBI

Read more here: » Traumatic brain injury: Encyclopedia II - Traumatic brain injury - Signs and Symptoms of TBI

biochemical cascade: Encyclopedia II - Stroke - Prevention

Prevention is an important public health concern. Identification of patients with treatable risk factors for stroke is paramount. Treatment of risk factors in patients who have already had strokes (secondary prevention) is also very important as they are at high risk of subsequent events compared with those who have never had a stroke. Medication or drug therapy is the most common method of stroke prevention. Aspirin (usually at a low dose of 75 mg) is recommended for the primary and secondary prevention of stroke, and treating hypertension is another way to mo ...

See also:

Stroke, Stroke - Types of stroke, Stroke - Ischemic stroke, Stroke - Hemorrhagic stroke, Stroke - Watershed stroke, Stroke - Rarer types of stroke, Stroke - Causes, Stroke - Ischemic stroke, Stroke - Hemorrhagic stroke, Stroke - Watershed stroke, Stroke - Signs and symptoms, Stroke - Diagnosis, Stroke - Pathophysiology, Stroke - Prevention, Stroke - Treatment, Stroke - Early assessment, Stroke - Ischemic stroke, Stroke - Hemorrhagic stroke, Stroke - Care and rehabilitation, Stroke - Prognosis, Stroke - Risk factors, Stroke - History

Read more here: » Stroke: Encyclopedia II - Stroke - Prevention

biochemical cascade: Encyclopedia II - Subdural hematoma - Risk factors

Factors increasing the risk of a subdural hematoma include very young or very old age. As the brain shrinks with age, the subdural space enlarges and the veins that traverse the space must travel over a wider distance, making them more vulnerable to tears. This and the fact that the elderly have more brittle veins make chronic subdural bleeds more common in older patients (Downie, 2001). Infants, too, have larger subdural spaces and are more predisposed to subdural bleeds than are young adults (Wagner, 2004). Other risk factors for subdural bleeds include taking blood thinners (antic ...

See also:

Subdural hematoma, Subdural hematoma - Causes, Subdural hematoma - Signs and symptoms, Subdural hematoma - Features, Subdural hematoma - Subtypes, Subdural hematoma - Pathophysiology, Subdural hematoma - Treatment, Subdural hematoma - Risk factors, Subdural hematoma - Prevention

Read more here: » Subdural hematoma: Encyclopedia II - Subdural hematoma - Risk factors

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