Ataxia (from Greek ataxiā, meaning failure to put in order) is unsteady and clumsy motion of the limbs or trunk due to a failure of the fine coordination of muscle movements. Ataxia often occurs when parts of the nervous system that control movement are damaged. People with ataxia experience a failure of muscle control in their arms and legs, resulting in a lack of balance and coordination or a disturbance of gait. While the term ataxia is primarily used to describe this set of symptoms, it is sometimes also used to refer to a family of disorde ...

Read more here: » Ataxia: Encyclopedia - Ataxia

See also:

Spinocerebellar ataxia, Spinocerebellar ataxia - Types, Spinocerebellar ataxia - Notes, Spinocerebellar ataxia - Technical description

Read more here: » Spinocerebellar ataxia: Encyclopedia II - Spinocerebellar ataxia - Types

So far there appear to be three forms of AT: Pure AT where patients present with all/most of the diagnostic symptoms. Attenuated AT where sufferers do not possess all of the diagnostic symptoms. Carrier AT where individuals with a single ATM mutation show an increased risk of cancer (known since the 1970’s). These are sometimes classified into ‘types’ from I to IV. Type I is the classic syndrome with all manifestations. Type II lacks some of the typical findings but sho ...

See also:

Ataxia telangiectasia, Ataxia telangiectasia - Definition/Criteria, Ataxia telangiectasia - Classification, Ataxia telangiectasia - Differential Diagnosis, Ataxia telangiectasia - Clinical Description, Ataxia telangiectasia - Management, Ataxia telangiectasia - Diagnostic Methods, Ataxia telangiectasia - Aetiology, Ataxia telangiectasia - Clinical Aspects, Ataxia telangiectasia - Prognosis, Ataxia telangiectasia - Epidemiology/ Prevalence, Ataxia telangiectasia - Molecular Diagnosis, Ataxia telangiectasia - Genetic Counselling, Ataxia telangiectasia - Antenatal Diagnosis

Read more here: » Ataxia telangiectasia: Encyclopedia II - Ataxia telangiectasia - Classification

Automatic Writing is an album by Ataxia released in 2004. Ataxia consists of John Frusciante, Josh Klinghoffer (Bicycle Thief) and Joe Lally (Fugazi). The band recorded 10 songs, approximately 90 minutes of music, over a period of 4 days, playing two shows amidst the recording process. The second Ataxia album was recorded during the same session as Automatic Writing and will be released as soon as Frusciante and Klinghoffer allow it. Ataxia 2 Ethiopian Song The Empty's Resp ...

Including:

Automatic Writing album - Track Listing Automatic Writing album - Personnel

Read more here: » Automatic Writing album: Encyclopedia - Automatic Writing album

ethosuximide Ethosuximide is a succinimide anticonvulsant, used mainly in absence seizures. It is sold by Pfizer under the name Zarontin®. Ethosuximide - Adverse Effects. Ethosuximide - Central Nervous System. drowsiness mental confusion insomnia nervousness headache euphoria ataxia hiccups impaired concentration irritability hyperactivity

AT is an autosomal recessive disorder caused by mutations in the ATM gene located on chromosome 11q22-23 (OMIM 208900). It was characterised in June of 1995 and is made up of 66 exons spread across 150kb of genomic DNA. It encodes a 13kb mature transcript with an open reading frame of 9168 nucleotides. The ATM protein is about 370kDa long and is ubiquitously expressed and is localised to the cell nucleus. The ATM protein is a large serine-threonine kinase thought to play a role in regulating cell cycle checkpoints, repair of double stranded ...

See also:

Ataxia telangiectasia, Ataxia telangiectasia - Definition/Criteria, Ataxia telangiectasia - Classification, Ataxia telangiectasia - Differential Diagnosis, Ataxia telangiectasia - Clinical Description, Ataxia telangiectasia - Management, Ataxia telangiectasia - Diagnostic Methods, Ataxia telangiectasia - Aetiology, Ataxia telangiectasia - Clinical Aspects, Ataxia telangiectasia - Prognosis, Ataxia telangiectasia - Epidemiology/ Prevalence, Ataxia telangiectasia - Molecular Diagnosis, Ataxia telangiectasia - Genetic Counselling, Ataxia telangiectasia - Antenatal Diagnosis

Read more here: » Ataxia telangiectasia: Encyclopedia II - Ataxia telangiectasia - Aetiology

Nijmegen syndrome, also known as ataxia telangiectasia variant 1, is a very rare syndrome which could be considered as a differential diagnosis to AT. People with Nijmegen syndrome show the same immunodeficiency, radiosensitivity and risk of cancer as AT but do not have any ataxia or oculo-cutaneous telangiectasia. Nijmegen syndrome sufferers also show microcephaly. The gene associated with Nijmegen syndrome is known to be located on 8q21 and thought to play a similar role to the ATM gene. In the ear ...

See also:

Ataxia telangiectasia, Ataxia telangiectasia - Definition/Criteria, Ataxia telangiectasia - Classification, Ataxia telangiectasia - Differential Diagnosis, Ataxia telangiectasia - Clinical Description, Ataxia telangiectasia - Management, Ataxia telangiectasia - Diagnostic Methods, Ataxia telangiectasia - Aetiology, Ataxia telangiectasia - Clinical Aspects, Ataxia telangiectasia - Prognosis, Ataxia telangiectasia - Epidemiology/ Prevalence, Ataxia telangiectasia - Molecular Diagnosis, Ataxia telangiectasia - Genetic Counselling, Ataxia telangiectasia - Antenatal Diagnosis

Read more here: » Ataxia telangiectasia: Encyclopedia II - Ataxia telangiectasia - Differential Diagnosis

→ Somnolence → Ataxia → Anterograde amnesia ...

See also:

Carisoprodol, Carisoprodol - Chemistry, Carisoprodol - Effects, Carisoprodol - Pharmacokinetics

Read more here: » Carisoprodol: Encyclopedia II - Carisoprodol - Effects

Anita Harding (September 17, 1952 - September 11, 1995) was a British neurologist. Anita Harding made several significant contributions especially in the field of inherited neurologic disorders. Her major achievements are the classification of the peripheral neuropathies and hereditary ataxias, the first identification of a mitochondrial DNA mutation in human disease and the identification of trinucleotide repeats in degenerative neurologic diseases (e.g. Huntington's disease). She has also worked extensively on the popula ...

Read more here: » Anita Harding: Encyclopedia - Anita Harding

Flurazepam Flurazepam is a long-acting benzodiazepine which is used as a sedative. It is marketed under the brand name Dalmane. It has the longest half-life of all of the benzodiazepines (40-250 hours), and may stay in the bloodstream for up to four days. It is used for short-term treatment of patients with insomnia. The most common adverse effects are dizziness, drowsiness, lightheadedness and ataxia. Flurazepam is a Schedule IV drug un ...

Including:

Flurazepam - References and End Notes

Read more here: » Flurazepam: Encyclopedia - Flurazepam

At therapeutic doses, phenytoin produces horizontal gaze nystagmus, which is harmless but occasionally tested for by law enforcement as a marker for drunkenness (which can also produce nystagmus). At toxic doses, patients experience sedation, cerebellar ataxia, and ophthalmoparesis, as well as paradoxical seizures. Idiosyncratic side effects of phenytoin, as with other anticonvulsants, i ...

See also:

Phenytoin, Phenytoin - History, Phenytoin - Side-effects, Phenytoin - Legal issues

Read more here: » Phenytoin: Encyclopedia II - Phenytoin - Side-effects

List of diseases starting with A - Ana-Ane. Anablephobia Anaphylaxis Anaplastic thyroid cancer Andersen's disease Andre syndrome Androgen insensitivity syndrome (AIS) Anemia sideroblastic spinocerebellar ataxia Anemia, Diamond-Blackfan Anemia, Hypoplastic, Congenital Anemia, Pernicious Anemia, Sideroblastic Anemia Anemophobia Anencephaly spina bifida X linked Anencephaly Aneurysm of sinus of Valsalva See also:

List of diseases starting with A, List of diseases starting with A - Aa-Ab, List of diseases starting with A - Ac, List of diseases starting with A - Aca-Acc, List of diseases starting with A - Ach-Ack, List of diseases starting with A - Acn-Acq, List of diseases starting with A - Acr, List of diseases starting with A - Act, List of diseases starting with A - Acu, List of diseases starting with A - Acy, List of diseases starting with A - Ad, List of diseases starting with A - Ada-Adi, List of diseases starting with A - Ado-Adr, List of diseases starting with A - Adu, List of diseases starting with A - Ae-Ah, List of diseases starting with A - Ai-Ak, List of diseases starting with A - Al, List of diseases starting with A - Ala-Alc, List of diseases starting with A - Ald-Alk, List of diseases starting with A - All, List of diseases starting with A - Alo, List of diseases starting with A - Alp-Alz, List of diseases starting with A - Am, List of diseases starting with A - Ama-Ame, List of diseases starting with A - Ami-Amy, List of diseases starting with A - An, List of diseases starting with A - Ana-Ane, List of diseases starting with A - Ang, List of diseases starting with A - Ani-Ank, List of diseases starting with A - Ann, List of diseases starting with A - Ano, List of diseases starting with A - Ans-Ant, List of diseases starting with A - Ao, List of diseases starting with A - Ap, List of diseases starting with A - Ape-App, List of diseases starting with A - Apr-Apu, List of diseases starting with A - Aq, List of diseases starting with A - Ar, List of diseases starting with A - Ara-Aro, List of diseases starting with A - Arr, List of diseases starting with A - Art, List of diseases starting with A - Ary, List of diseases starting with A - As, List of diseases starting with A - At, List of diseases starting with A - Au-Az

Read more here: » List of diseases starting with A: Encyclopedia II - List of diseases starting with A - An

Spironolactone can cause gastrointestinal problems fairly often. Since it also affects steroid receptors elsewhere in the body, it can cause gynecomastia, menstrual irregularities and testicular atrophy. Other side effects include ataxia, impotence, drowsiness and rashes. A carcinogenic effect has been demonstrated in rats. ...

See also:

Spironolactone, Spironolactone - Mechanism of action, Spironolactone - Pharmacokinetics, Spironolactone - Side effects

Read more here: » Spironolactone: Encyclopedia II - Spironolactone - Side effects

Patients with cerebellar dysfunction experience problems in walking, balance, and accurate hand and arm movement. Recent brain imaging studies using functional magnetic resonance imaging (fMRI) show that the cerebellum is important for language processing and selective attention. Neuropsychiatric disorders such as dyslexia and autism appear to be associated with a deficiency in the cerebellum, which may also play a role in the development of certain ataxias, including a form of cerebral palsy. Spinocerebellar ataxia patients suffer cerebella ...

See also:

Cerebellum, Cerebellum - General features, Cerebellum - Development and evolution, Cerebellum - Anatomy, Cerebellum - Divisions, Cerebellum - Deep nuclei, Cerebellum - Cortical layers, Cerebellum - Peduncles, Cerebellum - Blood supply, Cerebellum - Dysfunction, Cerebellum - Lesions of the cerebellum, Cerebellum - Ischemia and thrombosis, Cerebellum - Theories about cerebellar function, Cerebellum - Cerebellar modeling

Read more here: » Cerebellum: Encyclopedia II - Cerebellum - Dysfunction

All general contraindications to benzodiazepines apply. These are: myasthenia gravis acute intoxications with alcohol, narcotics, and psychoactive drugs ataxia severe respiratory insufficience severe liver insufficience (drug elimination is greatly decreased) attacks of apnea during sleep children and adolescents (< 18 yrs. of age) : treatment usually not indicated, except treatment of epilepsy, and pre-/postoperative treatment; extended cli ...

See also:

Clonazepam, Clonazepam - Common uses, Clonazepam - Contraindications, Clonazepam - Side Effects, Clonazepam - Dosage recommendations, Clonazepam - Taking clonazepam, Clonazepam - Discontinuation effects, Clonazepam - Dose Forms, Clonazepam - Overdose

Read more here: » Clonazepam: Encyclopedia II - Clonazepam - Contraindications

There are several factors that can affect the quality of speech as such. Among these are: Diseases and disorders of the lungs or the vocal cords, including paralysis, respiratory infections, and cancers of the lungs and throat. Diseases and disorders of the brain, including alogia, aphasias and speech processing disorders, where impaired perception of the message (as opposed to the actual sound) leads to poor speech production. Articulatory problems, such as stuttering, lisping, cleft palate, ataxia ...

See also:

Speech, Speech - Problems

Read more here: » Speech: Encyclopedia II - Speech - Problems

Symptoms include: opsoclonus: myoclonus ataxia intention tremor dysphasia dysarthria mutism hypotonia lethargy irritability or malaise drooling strabismus vomiting Sleep problems ("night rages"). About half of all OMS cases occur in association with neuroblastoma. ...

See also:

Opsoclonus myoclonus syndrome, Opsoclonus myoclonus syndrome - Nomenclature, Opsoclonus myoclonus syndrome - Signs and symptoms, Opsoclonus myoclonus syndrome - Diagnosis, Opsoclonus myoclonus syndrome - Cause, Opsoclonus myoclonus syndrome - Disease course and clinical subtypes, Opsoclonus myoclonus syndrome - Factors triggering a relapse, Opsoclonus myoclonus syndrome - Prognosis, Opsoclonus myoclonus syndrome - Treatment

Read more here: » Opsoclonus myoclonus syndrome: Encyclopedia II - Opsoclonus myoclonus syndrome - Signs and symptoms

A particularly devastating form of paraneoplastic syndromes is a group of disorders classified as paraneoplastic neurological disorders (PNDs). These paraneoplastic disorders affect the brain and central nervous system and they are degenerative. Symptoms of paraneoplastic neurological disorders include ataxia (difficulty with walking and balance), dizziness, nystagmus (rapid uncontrolled eye movements), speech problems, mental changes, and motor deterioration. The most common cancers associated with paraneoplastic neurological disorders are breast, ovarian and lung cancer ...

See also:

Paraneoplastic phenomenon, Paraneoplastic phenomenon - Examples, Paraneoplastic phenomenon - Neurological, Paraneoplastic phenomenon - Organisations, Paraneoplastic phenomenon - External link

Read more here: » Paraneoplastic phenomenon: Encyclopedia II - Paraneoplastic phenomenon - Neurological

Ethosuximide - Central Nervous System. drowsiness mental confusion insomnia nervousness headache euphoria ataxia hiccups impaired concentration irritability hyperactivity loss of taste night terrors paranoid psychosis increased l ...

See also:

Ethosuximide, Ethosuximide - Adverse Effects, Ethosuximide - Central Nervous System, Ethosuximide - Gastrointestinal, Ethosuximide - Genitourinary, Ethosuximide - Hematopoietic, Ethosuximide - Integumentary, Ethosuximide - Ocular, Ethosuximide - Complications, Ethosuximide - Drug Interactions, Ethosuximide - End Notes

Read more here: » Ethosuximide: Encyclopedia II - Ethosuximide - Adverse Effects

The clinical presentations is largely dependant on the age of onset of the disease. The most frequent type is the childhood-onset one, which normally occurs in males between the ages of 5 and 10 and is characterized by failure to develop, seizures, ataxia, adrenal insufficiency and degeneration of visual and auditory function. In the adolescent-onset form, the spinal cord dysfunction is more prominent and therefore is called adrenomyeloneuropathy or "AMD". The patients usually present with weakness and numbness of the limbs and urination or defecation problems. Most victims of this form are also males, although female ...

See also:

Adrenoleukodystrophy, Adrenoleukodystrophy - Symptoms, Adrenoleukodystrophy - Diagnosis, Adrenoleukodystrophy - Pathophysiology, Adrenoleukodystrophy - Treatment, Adrenoleukodystrophy - Famous patients

Read more here: » Adrenoleukodystrophy: Encyclopedia II - Adrenoleukodystrophy - Symptoms