Androgen insensitivity syndrome - Normal function of androgens and the androgen receptor

The gene, AR, for the human androgen receptor is located within the Xq11-12 area of the X chromosome. Effects of the AIS mutations behave as sex-linked recessive traits, causing minimal or no effects in 46,XX women. In other words, since 46,XX women have two X chromosomes, and hence two copies of the gene for the androgen receptor, no problems occur if one of the genes is defective. Since a 46,XY person has only a single X chromosome, a deleterious mutation of the androgen receptor gene on ...

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Androgen insensitivity syndrome, Androgen insensitivity syndrome - Genetics, inheritance, and incidence, Androgen insensitivity syndrome - Normal function of androgens and the androgen receptor, Androgen insensitivity syndrome - Prenatal effects of testosterone in 46, XY fetus, Androgen insensitivity syndrome - Early postnatal effects of testosterone in 46, XY infants, Androgen insensitivity syndrome - Pubertal effects of testosterone in 46, XY children, Androgen insensitivity syndrome - Problems produced by androgen insensitivity, Androgen insensitivity syndrome - 1. Complete AIS, Androgen insensitivity syndrome - 2. Incomplete or partial AIS, Androgen insensitivity syndrome - 3. Reifenstein syndrome, Androgen insensitivity syndrome - 4. Infertile male syndrome, Androgen insensitivity syndrome - 5. Undervirilized fertile male syndrome, Androgen insensitivity syndrome - 6. X-linked spinal and bulbar atrophy syndrome

Read more here: » Androgen insensitivity syndrome: Encyclopedia II - Androgen insensitivity syndrome - Genetics, inheritance, and incidence

Androgen insensitivity syndrome (AIS, or "Androgen resistance syndrome") is a set of disorders of sexual differentiation that results from mutations of the gene encoding the androgen receptor. It has also been called androgen resistance in the medical literature. The nature of the resulting problem varies according to the structure and sensitivity of the abnormal receptor. Most of the forms of AIS involve variable degrees of undervirilization and/or infertility in XY persons of either sex. A woman with complete androgen ...

Including:

• Androgen insensitivity syndrome - Genetics inheritance and incidence
• Androgen insensitivity syndrome - Normal function of androgens and the androgen receptor
• Androgen insensitivity syndrome - Prenatal effects of testosterone in 46XY fetus
• Androgen insensitivity syndrome - Early postnatal effects of testosterone in 46XY infants
• Androgen insensitivity syndrome - Pubertal effects of testosterone in 46XY children
• Androgen insensitivity syndrome - Problems produced by androgen insensitivity
• Androgen insensitivity syndrome - 1. Complete AIS
• Androgen insensitivity syndrome - 2. Incomplete or partial AIS
• Androgen insensitivity syndrome - 3. Reifenstein syndrome
• Androgen insensitivity syndrome - 4. Infertile male syndrome
• Androgen insensitivity syndrome - 5. Undervirilized fertile male syndrome
• Androgen insensitivity syndrome - 6. X-linked spinal and bulbar atrophy syndrome

Read more here: » Androgen insensitivity syndrome: Encyclopedia - Androgen insensitivity syndrome

Understanding the effects of androgen insensitivity begins with an understanding of the normal effects of testosterone in male and female development. The principal mammalian androgens are testosterone and its more potent metabolite, dihydrotestosterone (DHT). The androgen receptor (AR) is a large protein of at least 910 amino acids. Each molecule consists of a portion which binds the androgen, a zinc finger portion t ...

See also:

Androgen insensitivity syndrome, Androgen insensitivity syndrome - Genetics inheritance and incidence, Androgen insensitivity syndrome - Normal function of androgens and the androgen receptor, Androgen insensitivity syndrome - Prenatal effects of testosterone in 46XY fetus, Androgen insensitivity syndrome - Early postnatal effects of testosterone in 46XY infants, Androgen insensitivity syndrome - Pubertal effects of testosterone in 46XY children, Androgen insensitivity syndrome - Problems produced by androgen insensitivity, Androgen insensitivity syndrome - 1. Complete AIS, Androgen insensitivity syndrome - 2. Incomplete or partial AIS, Androgen insensitivity syndrome - 3. Reifenstein syndrome, Androgen insensitivity syndrome - 4. Infertile male syndrome, Androgen insensitivity syndrome - 5. Undervirilized fertile male syndrome, Androgen insensitivity syndrome - 6. X-linked spinal and bulbar atrophy syndrome

Read more here: » Androgen insensitivity syndrome: Encyclopedia II - Androgen insensitivity syndrome - Normal function of androgens and the androgen receptor

The gene, AR, for the human androgen receptor is located within the Xq11-12 area of the X chromosome. Effects of the AIS mutations behave as sex-linked recessive traits, causing minimal or no effects in 46,XX women. In other words, since 46,XX women have two X chromosomes, and hence two copies of the gene for the androgen receptor, no problems occur if one of the genes is defective. Since a 46,XY person has only a single X chromosome, a deleterious mutation of the androgen receptor gene on th ...

See also:

Androgen insensitivity syndrome, Androgen insensitivity syndrome - Genetics inheritance and incidence, Androgen insensitivity syndrome - Normal function of androgens and the androgen receptor, Androgen insensitivity syndrome - Prenatal effects of testosterone in 46XY fetus, Androgen insensitivity syndrome - Early postnatal effects of testosterone in 46XY infants, Androgen insensitivity syndrome - Pubertal effects of testosterone in 46XY children, Androgen insensitivity syndrome - Problems produced by androgen insensitivity, Androgen insensitivity syndrome - 1. Complete AIS, Androgen insensitivity syndrome - 2. Incomplete or partial AIS, Androgen insensitivity syndrome - 3. Reifenstein syndrome, Androgen insensitivity syndrome - 4. Infertile male syndrome, Androgen insensitivity syndrome - 5. Undervirilized fertile male syndrome, Androgen insensitivity syndrome - 6. X-linked spinal and bulbar atrophy syndrome

Read more here: » Androgen insensitivity syndrome: Encyclopedia II - Androgen insensitivity syndrome - Genetics inheritance and incidence