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Tuberculosis - The bacterium |  | Tuberculosis - The bacterium: Encyclopedia II - Tuberculosis - The bacterium |  | The cause of tuberculosis, Mycobacterium tuberculosis (MTB), is a slow-growing aerobic bacterium that divides every 16 to 20 hours. This is extremely slow compared to other bacteria, which tend to have division times measured in minutes (among the fastest growing bacteria is a strain of E. coli that can divide roughly every 20 minutes). It is not classified as either Gram-positive or Gram-negative because it does not have the chemical characteristics of either, although it contains peptidoglycan in their cell wall. If a Gram st ...
See also:Tuberculosis, Tuberculosis - Other names for the disease, Tuberculosis - The bacterium, Tuberculosis - The disease, Tuberculosis - Transmission, Tuberculosis - Pathogenesis, Tuberculosis - Progression, Tuberculosis - Drug resistance, Tuberculosis - Diagnosis, Tuberculosis - Treatment, Tuberculosis - Prevention, Tuberculosis - BCG vaccine, Tuberculosis - Tuberculosis vaccine, Tuberculosis - Animals, Tuberculosis - History, Tuberculosis - Tuberculosis in art literature history and film |  | | Tuberculosis, Tuberculosis - Animals, Tuberculosis - BCG vaccine, Tuberculosis - Diagnosis, Tuberculosis - Drug resistance, Tuberculosis - History, Tuberculosis - Other names for the disease, Tuberculosis - Pathogenesis, Tuberculosis - Prevention, Tuberculosis - Progression, Tuberculosis - The bacterium, Tuberculosis - The disease, Tuberculosis - Transmission, Tuberculosis - Treatment, Tuberculosis - Tuberculosis in art literature history and film, Tuberculosis - Tuberculosis vaccine, Abreugraphy, ATC code J04 Drugs for treatment of TB, Bacillus Calmette-Guérin (BCG), Heaf test, Leprosy and Buruli Ulcer, other mycobacteria caused disease, List of famous tuberculosis victims, Mycobacterium bovis causes TB in cattle, Nontuberculous mycobacteria, Tuberculosis classification, Tuberculosis diagnosis, Tuberculosis radiology, Tuberculosis treatment |  | |
|  |  | Tuberculosis: Encyclopedia II - Tuberculosis - The bacterium
Tuberculosis - The bacterium
The cause of tuberculosis, Mycobacterium tuberculosis (MTB), is a slow-growing aerobic bacterium that divides every 16 to 20 hours. This is extremely slow compared to other bacteria, which tend to have division times measured in minutes (among the fastest growing bacteria is a strain of E. coli that can divide roughly every 20 minutes). It is not classified as either Gram-positive or Gram-negative because it does not have the chemical characteristics of either, although it contains peptidoglycan in their cell wall. If a Gram stain is performed, it stains very weakly Gram-positive or not at all. It is a small rod-like bacillus which can withstand weak disinfectants and can survive in a dry state for weeks but, spontaneously, can only grow within a host organism (in vitro culture of M. tuberculosis took a long time to be achieved, but is nowadays a normal laboratory procedure).
MTB is identified microscopically by its staining characteristics: it retains certain stains after being treated with acidic solution, and is thus classified as an "acid-fast bacillus" or "AFB". In the most common staining technique, the Ziehl-Neelsen stain, AFB are stained a bright red which stands out clearly against a blue background. Acid-fast bacilli can also be visualized by fluorescent microscopy, and by auramine-rhodamine stain.
The M. tuberculosis complex includes 3 other mycobacteria which can cause tuberculosis: M. bovis, M. africanum, and M. microti. The first two are very rare causes of disease and the last one does not cause human disease.
Nontuberculous mycobacteria (NTM) are other mycobacteria (besides M. leprae which causes leprosy) which may cause pulmonary disease resembling TB, lymphadenitis, skin disease, or disseminated disease. These include Mycobacterium avium, M. kansasii, and others.
Other related archives1820s, 1839, 1859, 1882, 1885, 1905, 1906, 1913, 1921, 1970s, 1980s, 19th, 2005, 20th, A Moveable Feast, AIDS, ATC code J04, Abreugraphy, Albert Calmette, Alice Neel, American, American Lung Association, Australian, BCG, Bacillus Calmette-Guérin, Bacillus of Calmette and Guerin, Bleak House, Blue Mountains, Buruli Ulcer, California, Camille Guerin, Carol Burnett, Carrie Hamilton, Charles Dickens, Charlotte Bronte, Christmas Seals, David Brainerd, E. coli, Edgar Allan Poe, Edvard Munch, Emily Bronte, Ernest Hemingway, Eugene O'Neill, Fathers and Sons, Finding Neverland, France, Frederic Chopin, Fyodor Dostoevsky, Germany, Goth, Gram-negative, Gram-positive, Great Britain, HIV, Hayao Miyazaki, Heaf test, Heavenly Creatures, Hippocrates, Hocus Pocus, Ikedaya Affair, India, Ivan Turgenev, J. L. Schönlein, JAMA, Jane Eyre, Jimmie Rodgers, John "Doc" Holliday, John Bunyan, John Keats, John Piper, Jonathan Edwards, Juliet Hulme, July 18, Kurt Vonnegut, La Traviata, La bohème, Leprosy, List of famous tuberculosis victims, Long Day's Journey Into Night, M. bovis, M. leprae, Mammoth Cave, March 24, Mark Helprin, Medical Research Council, Miliary tuberculosis, Moulin Rouge!, My Life as a Dog, My Neighbor Totoro, Mycobacterium bovis, Mycobacterium tuberculosis, National Institute of Allergy and Infectious Diseases, New Zealand, Nicholas Nickleby, Nobel Prize in physiology or medicine, Nontuberculous mycobacteria, Northern Ireland, Octave Mirbeau, Okita Soji, Pauline Parker, Peter Jackson, Poland, Pott's disease, Prosector's wart, Puccini, Republic of Ireland, Robert Koch, Russian literature, Scrofula, Shinsengumi, Sylvia Plath, The Americas, The Bell Jar, The Idiot, The Magic Mountain, The Possessed, The Twilight Samurai, Thomas Mann, Tombstone, Tuberculosis classification, Tuberculosis diagnosis, Tuberculosis radiology, Tuberculosis treatment, USA, United Kingdom, United States, Val Kilmer, Van Morrison, Verdi's, Winter's Tale, World Health Organization, World War II, Ziehl-Neelsen stain, acid-fast bacillus, advance market commitments, aerobic, anatomists, antibiotics, antiquity, asymptomatic, auramine-rhodamine stain, autobiographical, bacillus, bacterium, badgers, bones, bronchi, butchers, caseous necrosis, central nervous system, chemotherapy, circulatory system, clinical trials, courtesan, cytokine, developing countries, disease, disinfectants, drug-resistant, dry state, endemic, fibrosis, genitourinary system, gerbils, glycerine, granuloma, granulomas, gunslinger, hemoptysis, infection, infectious diseases, infectiousness, interferon gamma, joints, leprosy, lungs, lymph nodes, lymphatic system, malaria, mammals, meningitis, miliary tuberculosis, mummies, mycobacteria, nontuberculous mycobacteria, notifiable disease, novelty pets, pasteurization, pathologists, peptidoglycan, pet skunks, prevalent, public health, pulmonary alveoli, recombinant, sanatoria, sanatorium, scrofula, spittoons, streptomycin, surgeons, tuberculosis diagnosis, tuberculosis radiology, tuberculosis treatment, tumor necrosis factor-alpha, vaccine, vector species, veterinarians, virulence, von Pirquet
 Adapted from the Wikipedia article "The bacterium", under the G.N U Free Docmentation License. Please also see http://en.wikipedia.org/wiki |
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