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Pituitary adenoma - Types | | Pituitary adenoma - Types: Encyclopedia II - Pituitary adenoma - Types | | Pituitary tumors were, historically, classed as basophilic, acidophilic, or chromophobic on the basis of whether or not they took up the stains hematoxylin and eosin. This classification has fallen into disuse, in favor of a classification based on what type of hormone is secreted by the tumor (though tumors which do not secrete any active hormone ("non-functioning tumors") are still sometimes called "chromophobic").
At present, classification of pituitary tumors is based on plasma hormone levels or immunohistochemical staining:
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See also:Pituitary adenoma, Pituitary adenoma - Types, Pituitary adenoma - Diagnosis, Pituitary adenoma - Treatment | | | Pituitary adenoma, Pituitary adenoma - Diagnosis, Pituitary adenoma - Treatment, Pituitary adenoma - Types | | |
| | | Pituitary adenoma: Encyclopedia II - Pituitary adenoma - Types
Pituitary adenoma - Types
Pituitary tumors were, historically, classed as basophilic, acidophilic, or chromophobic on the basis of whether or not they took up the stains hematoxylin and eosin. This classification has fallen into disuse, in favor of a classification based on what type of hormone is secreted by the tumor (though tumors which do not secrete any active hormone ("non-functioning tumors") are still sometimes called "chromophobic").
At present, classification of pituitary tumors is based on plasma hormone levels or immunohistochemical staining:
- corticotrophic adenomas secrete adrenocorticotropic hormone (ACTH) and pro-opiomelanocortin (POMC)
- somatotrophic adenomas secrete growth hormone (GH)
- thyrotrophic adenomas secrete thyroid-stimulating hormone (TSH)
This is a rare tumor type, making up <1% of all pituitary adenomas. TSH secretion from these tumors can cause hyperthroidism.[1]
- gonadotrophic adenomas secrete luteinizing hormone (LH), follicle-stimulating hormone (FSH) and their subunits
- lactrotrophic adenomas or prolactinomas secrete prolactin
- null cell adenomas do not secrete hormones, but may stain positive for synaptophysin
Other related archivesACTH, CT scan, Cushing's disease, FSH, GH, LH, MRI, POMC, TSH, acidophilic, acromegaly, amenorrhea, antagonist, basophilic, bromocriptine, eosin, galactorrhea, hematoxylin, hormone, hypogonadism, impotence, infertility, neoplasms, octreotide, a long-acting somatostatin analog, optic nerve, pituitary gland, progesterone, prolactin, prolactinomas, radiation therapy, synaptophysin, tumors
 Adapted from the Wikipedia article "Types", under the G.N U Free Docmentation License. Please also see http://en.wikipedia.org/wiki |
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