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Loop diuretic - Adverse effects

Loop diuretic - Adverse effects: Encyclopedia II - Loop diuretic - Adverse effects

The most common adverse drug reactions (ADRs) are dose-related and relate to the effect of loop diuretics on diuresis and electrolyte balance. Common ADRs include: hyponatremia, hypokalemia, hypomagnesemia, dehydration, hyperuricemia, gout, dizziness, postural hypotension, syncope (Rossi, 2004). Infrequent ADRs include: dyslipidemia, increased serum creatinine concentration, hypocalcemia, rash (Rossi, 2004). Ototoxicity (damage to the ear) is a serious, but rare ADR associated with use of loop diuretics. This may be limited to tinnitus and vert ...

See also:

Loop diuretic, Loop diuretic - Mechanism of action, Loop diuretic - Clinical use, Loop diuretic - Loop diuretic resistance, Loop diuretic - Adverse effects, Loop diuretic - Examples of loop diuretics

Loop diuretic, Loop diuretic - Adverse effects, Loop diuretic - Clinical use, Loop diuretic - Examples of loop diuretics, Loop diuretic - Loop diuretic resistance, Loop diuretic - Mechanism of action

Loop diuretic: Encyclopedia II - Loop diuretic - Adverse effects



Loop diuretic - Adverse effects

The most common adverse drug reactions (ADRs) are dose-related and relate to the effect of loop diuretics on diuresis and electrolyte balance.

Common ADRs include: hyponatremia, hypokalemia, hypomagnesemia, dehydration, hyperuricemia, gout, dizziness, postural hypotension, syncope (Rossi, 2004).

Infrequent ADRs include: dyslipidemia, increased serum creatinine concentration, hypocalcemia, rash (Rossi, 2004).

Ototoxicity (damage to the ear) is a serious, but rare ADR associated with use of loop diuretics. This may be limited to tinnitus and vertigo, but may result in deafness in serious cases.

Loop diuretics may also precipitate renal failure in patients concomitantly taking an NSAID and an ACE inhibitor -- the so-called "triple whammy" effect (Thomas, 2000).




Adapted from the Wikipedia article "Adverse effects", under the G.N U Free Docmentation License. Please also see http://en.wikipedia.org/wiki

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