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Hydromorphone - Details | | Hydromorphone - Details: Encyclopedia II - Hydromorphone - Details | | Hydromorphone, a semi-synthetic μ-opioid agonist, is a hydrogenated ketone of morphine and shares the pharmacologic properties typical of opioid analgesics. Hydromorphone and related opioids produce their major effects on the central nervous system and gastrointestinal tract. These include analgesia, drowsiness, mental clouding, changes in mood, euphoria or dysphoria, respiratory depression, cough suppression, decreased gastrointestinal motility, nausea, vomiting, increased cerebrospinal fluid pressure, increased biliary pressure, pinpoint constriction of the pupils, increased parasympathe ...
See also:Hydromorphone, Hydromorphone - Overview, Hydromorphone - Details, Hydromorphone - Side Effects, Hydromorphone - Notes | | | Hydromorphone, Hydromorphone - Details, Hydromorphone - Notes, Hydromorphone - Overview, Hydromorphone - Side Effects | | |
| | | Hydromorphone: Encyclopedia II - Hydromorphone - Details
Hydromorphone - Details
Hydromorphone, a semi-synthetic μ-opioid agonist, is a hydrogenated ketone of morphine and shares the pharmacologic properties typical of opioid analgesics. Hydromorphone and related opioids produce their major effects on the central nervous system and gastrointestinal tract. These include analgesia, drowsiness, mental clouding, changes in mood, euphoria or dysphoria, respiratory depression, cough suppression, decreased gastrointestinal motility, nausea, vomiting, increased cerebrospinal fluid pressure, increased biliary pressure, pinpoint constriction of the pupils, increased parasympathetic activity and transient hyperglycemia.
CNS depressants, such as other opioids, anesthetics, sedatives, hypnotics, barbiturates, phenothiazines, chloral hydrate and glutethimide may enhance the depressant effects of hydromorphone. MAO inhibitors (including procarbazine), first-generation antihistamines (brompheniramine, diphenhydramine, chlorpheniramine), beta-blockers and alcohol may also enhance the depressant effect of hydromorphone. When combined therapy is contemplated, the dose of one or both agents should be reduced.
Other related archivesAlfentanil, Analgesics, Aspirin, Buprenorphine, Carfentanil, Celecoxib, Codeine, Codeinone, Dextropropoxyphene, Diclofenac, Diflunisal, Dihydrocodeine, Fentanyl, Heroin, Hydrocodone, Ibuprofen, Indomethacin, Ketoprofen, Ketorolac, MAO inhibitors, Meloxicam, Methadone, Morphine, Morphinone, Mu-opioid agonists, NSAIDs, Naproxen, Opiates, Oxycodone, Oxymorphone, Paracetamol (acetaminophen), Pethidine (Meperidine), Piroxicam, Remifentanil, Rofecoxib, Semisynthetic opioids, Sufentanil, Tetrahydrocannabinol, Tramadol, Valdecoxib, agonist, agonists, alcohol, analgesia, anesthetics, antihistamines, barbiturates, beta-blockers, brompheniramine, central nervous system, chloral hydrate, chlorpheniramine, diphenhydramine, drug, dysphoria, euphoria, gastrointestinal tract, glutethimide, hydrogenated, hyperglycemia, hypnotics, injury, ketone, morphine, opioid, opioid analgesics, opioids, pain, parasympathetic, phenothiazines, procarbazine, sedatives, surgery, μ-opioid
 Adapted from the Wikipedia article "Details", under the G.N U Free Docmentation License. Please also see http://en.wikipedia.org/wiki |
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