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Free-radical theory - Theory of disease | | Free-radical theory - Theory of disease: Encyclopedia II - Free-radical theory - Theory of disease | | One of the underlying concepts that guided Harman to his theory of aging was the involvement of free radicals in disease. Free radical damage within cells, and subsequent damage has been linked to a range of disorders including cancer, arthritis, atherosclerosis, Alzheimer's disease, and diabetes. this involvment is not at all surprising as free radical damage is an important aspect of phagocytosis, inflammation, and apoptosis. Cell suicide, or apoptosis, is the body's way of controlling cell death and involves free radicals and redox signalling. Redox factors play an even greater part in o ...
See also:Free-radical theory, Free-radical theory - Theory of disease, Free-radical theory - Evidence, Free-radical theory - Antioxidant therapy, Free-radical theory - Calorie restriction | | | Free-radical theory, Free-radical theory - Antioxidant therapy, Free-radical theory - Calorie restriction, Free-radical theory - Evidence, Free-radical theory - Theory of disease | | |
| | | Free-radical theory: Encyclopedia II - Free-radical theory - Theory of disease
Free-radical theory - Theory of disease
One of the underlying concepts that guided Harman to his theory of aging was the involvement of free radicals in disease. Free radical damage within cells, and subsequent damage has been linked to a range of disorders including cancer, arthritis, atherosclerosis, Alzheimer's disease, and diabetes. this involvment is not at all surprising as free radical damage is an important aspect of phagocytosis, inflammation, and apoptosis. Cell suicide, or apoptosis, is the body's way of controlling cell death and involves free radicals and redox signalling. Redox factors play an even greater part in other forms of cell death such as necrosis or autoschizis.
More recently, the relationship between disease and free radicals has led to the formulation of a greater generalisation. The free radical theory of disease states that disease is associated with abnormal levels of oxidation and the generation of free radical damage. In its strong form, the hypothesis states that all disease depends upon free radical damage. The weaker statement of the hypothesis is that disease generally involves free radical processes.
Other related archivesAlzheimer's disease, Caenorhabditis elegans, Calorie restriction, Reactive Oxygen Species, Robert Cathcart, Roy Walford, University of California, Los Angeles, Vitamin A, age, antioxidants, apoptosis, arthritis, atherosclerosis, atoms, average lifespan, cancer, catalase, chemical reactions, diabetes, electrons, free radical, fruits, hydrogen peroxide, inflammation, iron, maximum lifespan, mitochondria, molecules, necrosis, orthomolecular medicine, overexpression, oxidation, oxidizing, oxygen, phagocytosis, redox, reduction, rust, time, vegetables, vitamin C, vitamin E
 Adapted from the Wikipedia article "Theory of disease", under the G.N U Free Docmentation License. Please also see http://en.wikipedia.org/wiki |
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