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Dopamine - Dopamine and psychosis | | Dopamine - Dopamine and psychosis: Encyclopedia II - Dopamine - Dopamine and psychosis | | Disruption to the dopamine system has also been strongly linked to psychosis and schizophrenia. Dopamine neurons in the mesolimbic pathway are particularly associated with these conditions. This is partly due to the discovery of a class of drugs called the phenothiazines (which block D2 dopamine receptors) that can reduce psychotic symptoms, and partly due to the finding that drugs such as amphetamine and cocaine (which are known to greatly increase dopamine levels) can cause psychosis. Because of this, most modern antipsychotic m ...
See also:Dopamine, Dopamine - Biochemistry, Dopamine - Functions of dopamine in the brain, Dopamine - Role in movement, Dopamine - Role in cognition and frontal cortex function, Dopamine - Role in pleasure and motivation, Dopamine - Dopamine and psychosis, Dopamine - Therapeutic use, Dopamine - Major dopamine pathways | | | Dopamine, Dopamine - Biochemistry, Dopamine - Dopamine and psychosis, Dopamine - Functions of dopamine in the brain, Dopamine - Major dopamine pathways, Dopamine - Role in cognition and frontal cortex function, Dopamine - Role in movement, Dopamine - Role in pleasure and motivation, Dopamine - Therapeutic use, Addiction, Amphetamine, Antipsychotic, Catecholamine, Catechol-O-methyl transferase, Cocaine, Dopamine hypothesis of schizophrenia, Methylphenidate, Neurotransmitter, Parkinson's disease, Schizophrenia, Selegiline | | |
| | | Dopamine: Encyclopedia II - Dopamine - Dopamine and psychosis
Dopamine - Dopamine and psychosis
Disruption to the dopamine system has also been strongly linked to psychosis and schizophrenia. Dopamine neurons in the mesolimbic pathway are particularly associated with these conditions. This is partly due to the discovery of a class of drugs called the phenothiazines (which block D2 dopamine receptors) that can reduce psychotic symptoms, and partly due to the finding that drugs such as amphetamine and cocaine (which are known to greatly increase dopamine levels) can cause psychosis. Because of this, most modern antipsychotic medication is designed to block dopamine function to varying degrees. Blocking the D2 dopamine receptor is known to cause relapse in patients that have achieved remission from depression, and such blocking also counteracts the effectiveness of SSRI medication.
See the article on the dopamine hypothesis of psychosis for a wider discussion of this topic.
Other related archives2000, Addiction, Amphetamine, Antipsychotic, Arvid Carlsson, Attention deficit disorder, Catechol-O-methyl transferase, Catecholamine, Cocaine, DOPA, Dopamine hypothesis of schizophrenia, Dystonia, L-DOPA, Levodopa, Mesocortical pathway, Mesolimbic pathway, Methylphenidate, Neurotransmitter, Nigrostriatal pathway, Nobel Prize in Physiology or Medicine, Parkinson's disease, SSRI, Schizophrenia, Selegiline, Tuberoinfundibular pathway, action potential, adrenaline, amphetamine, amphetamines, anhedonia, antipsychotic, antipsychotics, aromatic-L-amino-acid decarboxylase, associated, attention, basal ganglia, benserazide, blood pressure, blood-brain barrier, brain, carbidopa, cardiac output, catechol-O-methyl transferase, catecholamine, central nervous system, cocaine, decarboxylation, desire, dopamine hypothesis of psychosis, dopamine receptor, dopamine receptors, dopamine transporter, epinephrine, food, frontal lobes, heart, hypothalamus, inotropic drug, medication, memory, mesolimbic pathway, nervous system, neurobiological, neurocognitive, neurohormone, neurons, neurotransmitter, nigrostriatal pathway, noradrenaline, norepinephrine, nucleus accumbens, phenothiazines, pituitary, pleasure, problem-solving, prolactin, psychosis, reinforcement, schizophrenia, sex, shock, striatum, sympathetic, tyrosine
 Adapted from the Wikipedia article "Dopamine and psychosis", under the G.N U Free Docmentation License. Please also see http://en.wikipedia.org/wiki |
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