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Cyclophosphamide - Side-effects |  | Cyclophosphamide - Side-effects: Encyclopedia II - Cyclophosphamide - Side-effects |  | Side-effects include chemotherapy-induced nausea and vomiting (CINV), bone marrow suppression, alopecia (hair loss) and lethargy. Hemorrhagic cystitis is a frequent complication, but this is prevented by adequate fluid intake and mesna (sodium 2-mercaptoethane sulfonate). Mesna is a sulfhydryl donor and binds acrolein.
Cyclophosphamide is itself carcinogenic, potentially causing transitional cell carc ...
See also:Cyclophosphamide, Cyclophosphamide - Uses, Cyclophosphamide - Pharmacokinetics, Cyclophosphamide - Mode of action, Cyclophosphamide - Side-effects, Cyclophosphamide - History, Cyclophosphamide - Reference |  | | Cyclophosphamide, Cyclophosphamide - History, Cyclophosphamide - Mode of action, Cyclophosphamide - Pharmacokinetics, Cyclophosphamide - Reference, Cyclophosphamide - Side-effects, Cyclophosphamide - Uses |  | |
|  |  | Cyclophosphamide: Encyclopedia II - Cyclophosphamide - Side-effects
Cyclophosphamide - Side-effects
Side-effects include chemotherapy-induced nausea and vomiting (CINV), bone marrow suppression, alopecia (hair loss) and lethargy. Hemorrhagic cystitis is a frequent complication, but this is prevented by adequate fluid intake and mesna (sodium 2-mercaptoethane sulfonate). Mesna is a sulfhydryl donor and binds acrolein.
Cyclophosphamide is itself carcinogenic, potentially causing transitional cell carcinoma of the bladder as a long-term complication.
Other related archivesALKYLATING AGENTS, ANTI-METABOLITES, ANTITUMOUR ANTIBIOTICS, Azathioprine, Bleomycin, Busulfan, Capecitabine, Carboplatin, Chemotherapeutic agents, Chlorambucil, Cisplatin, Cytarabine, Daunorubicin, Docetaxel, Doxorubicin, Epirubicin, Etoposide, Fludarabine, Fluorouracil, Gemcitabine, Hydroxyurea, Idarubicin, Irinotecan, Mechlorethamine, Melphalan, Methotrexate, Mitomycin, Mitoxantrone, Oxaliplatin, PLANT ALKALOIDS, Paclitaxel, Pemetrexed, Side-effects, Systemic lupus erythematosus, TOPOISOMERASE INHIBITORS, Vinblastine, Vincristine, Vinorelbine, acrolein, actively transported, alkylating agent, alopecia, autoimmune diseases, autoimmune disorders, bladder, bone marrow stem cells, bone marrow suppression, cancer, carcinogenic, carcinoma, chemotherapeutic, chemotherapy-induced nausea and vomiting, disease-modifying antirheumatic drugs, enzymatically, enzymes, epithelium, equilibrium, hemorrhagic cystitis, intestinal, lethargy, leukemia, liver, lupus nephritis, lymphomas, mesna, nitrogen mustard, oxidase, prodrug, tautomer
 Adapted from the Wikipedia article "Side-effects", under the G.N U Free Docmentation License. Please also see http://en.wikipedia.org/wiki |
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