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Cachexia

Cachexia: Encyclopedia - Cachexia

Cachexia is loss of weight, muscle wasting, fatigue, weakness and anorexia (not anorexia nervosa) in someone who is not actively trying to lose weight. It can be a sign of various underlying disorders; when a patient presents with cachexia, a doctor will generally consider the possibility of cancer, certain infectious diseases (e.g. tuberculosis) and some autoimmune disorders. Cachexia - Mechanism. The exact mechanism in which these diseases cause cachexia is poorly understood, but there is p ...

Including:

Cachexia, Cachexia - Mechanism, protein-energy malnutrition

Cachexia: Encyclopedia - Cachexia



Cachexia

Cachexia is loss of weight, muscle wasting, fatigue, weakness and anorexia (not anorexia nervosa) in someone who is not actively trying to lose weight. It can be a sign of various underlying disorders; when a patient presents with cachexia, a doctor will generally consider the possibility of cancer, certain infectious diseases (e.g. tuberculosis) and some autoimmune disorders.

Cachexia - Mechanism

The exact mechanism in which these diseases cause cachexia is poorly understood, but there is probably a role for inflammatory cytokines such as tumor necrosis factor alpha (TNF-α), which is also nicknamed cachectin for this reason.

Related malnutrition syndromes are kwashiorkor and marasmus, although these do not always have an underlying causative illness; they are most often symptomatic of severe malnutrition.

See also

  • protein-energy malnutrition



Adapted from the Wikipedia article "Cachexia", under the G.N U Free Docmentation License. Please also see http://en.wikipedia.org/wiki

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