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Antihistamine - Third-generation H1-receptor antagonists |  | Antihistamine - Third-generation H1-receptor antagonists: Encyclopedia II - Antihistamine - Third-generation H1-receptor antagonists |  | | These are the active enantiomer (levocetirizine, desloratadine) or metabolite (fexofenadine) derivatives of second-generation drugs intended to have increased efficacy with fewer adverse drug reactions. Indeed, fexofenadine is associated with a decreased risk of cardiac arrhythmia compared to terfenadine. However, there is little evidence for any advantage of levocetirizine or desloratadine, compared to cetirizine or loratadine respectively.
Antihistamine - SystemicSee also: Antihistamine, Antihistamine - Pharmacology, Antihistamine - Clinical use of antihistamines, Antihistamine - Indications, Antihistamine - Adverse drug reactions, Antihistamine - First-generation H1-receptor antagonists, Antihistamine - Ethylenediamines, Antihistamine - Ethanolamines, Antihistamine - Alkylamines, Antihistamine - Piperazines, Antihistamine - Tricyclics, Antihistamine - Common structural features of classical antihistamine, Antihistamine - Second-generation H1-receptor antagonists, Antihistamine - Systemic, Antihistamine - Topical, Antihistamine - Common structural features of non-sedating antihistamines, Antihistamine - Third-generation H1-receptor antagonists, Antihistamine - Systemic, Antihistamine - Other agents, Antihistamine - Inhibitors of histamine release, Antihistamine - H2-receptor antagonists, Antihistamine - H3- and H4-receptor antagonists, Antihistamine - Other agents with antihistaminergic activity |  | | Antihistamine, Antihistamine - Adverse drug reactions, Antihistamine - Alkylamines, Antihistamine - Clinical use of antihistamines, Antihistamine - Common structural features of classical antihistamine, Antihistamine - Common structural features of non-sedating antihistamines, Antihistamine - Ethanolamines, Antihistamine - Ethylenediamines, Antihistamine - First-generation H1-receptor antagonists, Antihistamine - H2-receptor antagonists, Antihistamine - H3- and H4-receptor antagonists, Antihistamine - Indications, Antihistamine - Inhibitors of histamine release, Antihistamine - Other agents, Antihistamine - Other agents with antihistaminergic activity, Antihistamine - Pharmacology, Antihistamine - Piperazines, Antihistamine - Second-generation H1-receptor antagonists, Antihistamine - Systemic, Antihistamine - Third-generation H1-receptor antagonists, Antihistamine - Topical, Antihistamine - Tricyclics, H2-receptor antagonist |  | |
|  |  | Antihistamine: Encyclopedia II - Antihistamine - Third-generation H1-receptor antagonists
Antihistamine - Third-generation H1-receptor antagonists
These are the active enantiomer (levocetirizine, desloratadine) or metabolite (fexofenadine) derivatives of second-generation drugs intended to have increased efficacy with fewer adverse drug reactions. Indeed, fexofenadine is associated with a decreased risk of cardiac arrhythmia compared to terfenadine. However, there is little evidence for any advantage of levocetirizine or desloratadine, compared to cetirizine or loratadine respectively.
Antihistamine - Systemic
- levocetirizine
- desloratadine
- fexofenadine
Other related archives5-HT receptors, Adverse drug reactions, CNS, Daniel Bovet, Epi-pen, Epinephrine, H2-receptor antagonist, Nobel Prize in Physiology or Medicine, OTC, acetylcholine receptor, adrenergic receptors, adverse drug reactions, allergen, allergic reactions, anaphylactic, anaphylaxis, angioedema, antagonists, antibodies, anticholinergic, antigen, antipsychotics, anxiety, astemizole, atopic dermatitis, basophils, brompheniramine, bronchoconstriction, cardiac arrhythmia, cardiac arrhythmias, central nervous system, cetirizine, chlorphenamine, cimetidine, clemastine, conjunctivitis, constipation, contact dermatitis, cromoglicate, cyclizine, dermatological, desloratadine, diarrhoea, dimenhydrinate, diphenhydramine, doxylamine, drug, euphoria, eyes, famotidine, fexofenadine, flushing, gastric, gastric acid, guanidine, guinea pig, hallucination, headache, histamine, histamine receptor, histamine receptors, hydroxyzine, hypotension, imidazole, insomnia, inverse agonists, isomerism, levocabastine, levocetirizine, loratadine, mast cells, meclizine, nausea, nose, pain, palpitations, parietal cells, phenothiazine, promethazine, pruritis, pruritus, psychosis, ranitidine, rhinitis, skin, tachycardia, terfenadine, thiourea, tinnitus, tricyclic antidepressants, triprolidine, urticaria, vasodilatation
 Adapted from the Wikipedia article "Third-generation H1-receptor antagonists", under the G.N U Free Docmentation License. Please also see http://en.wikipedia.org/wiki |
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