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Antihistamine - Third-generation H1-receptor antagonists

Antihistamine - Third-generation H1-receptor antagonists: Encyclopedia II - Antihistamine - Third-generation H1-receptor antagonists

These are the active enantiomer (levocetirizine, desloratadine) or metabolite (fexofenadine) derivatives of second-generation drugs intended to have increased efficacy with fewer adverse drug reactions. Indeed, fexofenadine is associated with a decreased risk of cardiac arrhythmia compared to terfenadine. However, there is little evidence for any advantage of levocetirizine or desloratadine, compared to cetirizine or loratadine respectively. Antihistamine - SystemicSee also:

Antihistamine, Antihistamine - Pharmacology, Antihistamine - Clinical use of antihistamines, Antihistamine - Indications, Antihistamine - Adverse drug reactions, Antihistamine - First-generation H1-receptor antagonists, Antihistamine - Ethylenediamines, Antihistamine - Ethanolamines, Antihistamine - Alkylamines, Antihistamine - Piperazines, Antihistamine - Tricyclics, Antihistamine - Common structural features of classical antihistamine, Antihistamine - Second-generation H1-receptor antagonists, Antihistamine - Systemic, Antihistamine - Topical, Antihistamine - Common structural features of non-sedating antihistamines, Antihistamine - Third-generation H1-receptor antagonists, Antihistamine - Systemic, Antihistamine - Other agents, Antihistamine - Inhibitors of histamine release, Antihistamine - H2-receptor antagonists, Antihistamine - H3- and H4-receptor antagonists, Antihistamine - Other agents with antihistaminergic activity

Antihistamine, Antihistamine - Adverse drug reactions, Antihistamine - Alkylamines, Antihistamine - Clinical use of antihistamines, Antihistamine - Common structural features of classical antihistamine, Antihistamine - Common structural features of non-sedating antihistamines, Antihistamine - Ethanolamines, Antihistamine - Ethylenediamines, Antihistamine - First-generation H1-receptor antagonists, Antihistamine - H2-receptor antagonists, Antihistamine - H3- and H4-receptor antagonists, Antihistamine - Indications, Antihistamine - Inhibitors of histamine release, Antihistamine - Other agents, Antihistamine - Other agents with antihistaminergic activity, Antihistamine - Pharmacology, Antihistamine - Piperazines, Antihistamine - Second-generation H1-receptor antagonists, Antihistamine - Systemic, Antihistamine - Third-generation H1-receptor antagonists, Antihistamine - Topical, Antihistamine - Tricyclics, H2-receptor antagonist

Antihistamine: Encyclopedia II - Antihistamine - Third-generation H1-receptor antagonists



Antihistamine - Third-generation H1-receptor antagonists

These are the active enantiomer (levocetirizine, desloratadine) or metabolite (fexofenadine) derivatives of second-generation drugs intended to have increased efficacy with fewer adverse drug reactions. Indeed, fexofenadine is associated with a decreased risk of cardiac arrhythmia compared to terfenadine. However, there is little evidence for any advantage of levocetirizine or desloratadine, compared to cetirizine or loratadine respectively.

Antihistamine - Systemic

  • levocetirizine
  • desloratadine
  • fexofenadine

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Adapted from the Wikipedia article "Third-generation H1-receptor antagonists", under the G.N U Free Docmentation License. Please also see http://en.wikipedia.org/wiki

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