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Antihistamine - Other agents

Antihistamine - Other agents: Encyclopedia II - Antihistamine - Other agents

Antihistamine - Inhibitors of histamine release. These agents appear to stabilise the mast cells to prevent degranulation and mediator release. cromoglicate (cromolyn) nedocromil Antihistamine - H2-receptor antagonists. Main article: H2-receptor antagonist Clinically-relevant histamine H2-receptors are found principally in the parietal cells of the gastric mucosa. H2-receptor "antagonists" are also inve ...

See also:

Antihistamine, Antihistamine - Pharmacology, Antihistamine - Clinical use of antihistamines, Antihistamine - Indications, Antihistamine - Adverse drug reactions, Antihistamine - First-generation H1-receptor antagonists, Antihistamine - Ethylenediamines, Antihistamine - Ethanolamines, Antihistamine - Alkylamines, Antihistamine - Piperazines, Antihistamine - Tricyclics, Antihistamine - Common structural features of classical antihistamine, Antihistamine - Second-generation H1-receptor antagonists, Antihistamine - Systemic, Antihistamine - Topical, Antihistamine - Common structural features of non-sedating antihistamines, Antihistamine - Third-generation H1-receptor antagonists, Antihistamine - Systemic, Antihistamine - Other agents, Antihistamine - Inhibitors of histamine release, Antihistamine - H2-receptor antagonists, Antihistamine - H3- and H4-receptor antagonists, Antihistamine - Other agents with antihistaminergic activity

Antihistamine, Antihistamine - Adverse drug reactions, Antihistamine - Alkylamines, Antihistamine - Clinical use of antihistamines, Antihistamine - Common structural features of classical antihistamine, Antihistamine - Common structural features of non-sedating antihistamines, Antihistamine - Ethanolamines, Antihistamine - Ethylenediamines, Antihistamine - First-generation H1-receptor antagonists, Antihistamine - H2-receptor antagonists, Antihistamine - H3- and H4-receptor antagonists, Antihistamine - Indications, Antihistamine - Inhibitors of histamine release, Antihistamine - Other agents, Antihistamine - Other agents with antihistaminergic activity, Antihistamine - Pharmacology, Antihistamine - Piperazines, Antihistamine - Second-generation H1-receptor antagonists, Antihistamine - Systemic, Antihistamine - Third-generation H1-receptor antagonists, Antihistamine - Topical, Antihistamine - Tricyclics, H2-receptor antagonist

Antihistamine: Encyclopedia II - Antihistamine - Other agents



Antihistamine - Other agents

Antihistamine - Inhibitors of histamine release

These agents appear to stabilise the mast cells to prevent degranulation and mediator release.

  • cromoglicate (cromolyn)
  • nedocromil

Antihistamine - H2-receptor antagonists

Main article: H2-receptor antagonist

Clinically-relevant histamine H2-receptors are found principally in the parietal cells of the gastric mucosa. H2-receptor "antagonists" are also inverse agonists, rather than true antagonists; and are used to reduce the secretion of gastric acid. Examples include cimetidine, ranitidine, and famotidine.

Antihistamine - H3- and H4-receptor antagonists

These are experimental agents and do not yet have a defined clinical use.

  • Thioperamide
  • Clobenpropit
  • Impromidine
      • Similar in structure to burimamide
      • imidazole ring
      • Polar moiety on the side chain - thiourea, isothiourea and guanidine
      • other substituents are highly variable

  • Thioperamide

Antihistamine - Other agents with antihistaminergic activity

Many drugs, used for other indications, possess unwanted antihistaminergic activity. These include tricyclic antidepressants, antipsychotics, etc.

Other related archives

5-HT receptors, Adverse drug reactions, CNS, Daniel Bovet, Epi-pen, Epinephrine, H2-receptor antagonist, Nobel Prize in Physiology or Medicine, OTC, acetylcholine receptor, adrenergic receptors, adverse drug reactions, allergen, allergic reactions, anaphylactic, anaphylaxis, angioedema, antagonists, antibodies, anticholinergic, antigen, antipsychotics, anxiety, astemizole, atopic dermatitis, basophils, brompheniramine, bronchoconstriction, cardiac arrhythmia, cardiac arrhythmias, central nervous system, cetirizine, chlorphenamine, cimetidine, clemastine, conjunctivitis, constipation, contact dermatitis, cromoglicate, cyclizine, dermatological, desloratadine, diarrhoea, dimenhydrinate, diphenhydramine, doxylamine, drug, euphoria, eyes, famotidine, fexofenadine, flushing, gastric, gastric acid, guanidine, guinea pig, hallucination, headache, histamine, histamine receptor, histamine receptors, hydroxyzine, hypotension, imidazole, insomnia, inverse agonists, isomerism, levocabastine, levocetirizine, loratadine, mast cells, meclizine, nausea, nose, pain, palpitations, parietal cells, phenothiazine, promethazine, pruritis, pruritus, psychosis, ranitidine, rhinitis, skin, tachycardia, terfenadine, thiourea, tinnitus, tricyclic antidepressants, triprolidine, urticaria, vasodilatation



Adapted from the Wikipedia article "Other agents", under the G.N U Free Docmentation License. Please also see http://en.wikipedia.org/wiki

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