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Addison's disease - Pathophysiology | | Addison's disease - Pathophysiology: Encyclopedia II - Addison's disease - Pathophysiology | | Eighty to ninety percent of cases of Addison's disease are said to be due to autoantibodies directed against adrenal cells containing 21-hydroxylase, an enzyme involved in the production of cortisol and aldosterone.
The remainder of cases are due to tuberculosis, HIV, sarcoidosis, amyloidosis, hemochromatosis, metastatic cancer to the adrenal glands, adrenal haemorrhage and congenital adrenal hyperplasia.
Addison's disease can be an expression of an autoimmune polyendocrine syndrome when autoimmune reactions against other organs are also present. In APS type 1, 70% suf ...
See also:Addison's disease, Addison's disease - Signs and symptoms, Addison's disease - Early signs, Addison's disease - Addisonian crisis, Addison's disease - Diagnosis, Addison's disease - Pathophysiology, Addison's disease - Treatment, Addison's disease - Famous patients, Addison's disease - In animals, Addison's disease - Reference | | | Addison's disease, Addison's disease - Addisonian crisis, Addison's disease - Diagnosis, Addison's disease - Early signs, Addison's disease - Famous patients, Addison's disease - In animals, Addison's disease - Pathophysiology, Addison's disease - Reference, Addison's disease - Signs and symptoms, Addison's disease - Treatment, Cushing's syndrome | | |
| | | Addison's disease: Encyclopedia II - Addison's disease - Pathophysiology
Addison's disease - Pathophysiology
Eighty to ninety percent of cases of Addison's disease are said to be due to autoantibodies directed against adrenal cells containing 21-hydroxylase, an enzyme involved in the production of cortisol and aldosterone.
The remainder of cases are due to tuberculosis, HIV, sarcoidosis, amyloidosis, hemochromatosis, metastatic cancer to the adrenal glands, adrenal haemorrhage and congenital adrenal hyperplasia.
Addison's disease can be an expression of an autoimmune polyendocrine syndrome when autoimmune reactions against other organs are also present. In APS type 1, 70% suffer from Addison's disease, while in type 2, 100% do.
Through these syndromes, Addison's is associated with hypothyroidism, diabetes mellitus (type 1),vitiligo, alopecia and celiac disease.
Other related archivesBearded Collie, British, Chihuahua, Cushing's syndrome, HIV, Jane Austen, John F. Kennedy, Thomas Addison, adrenal glands, adrenal insufficiency, adrenocorticotropic hormone, aldosterone, alopecia, amyloidosis, autoimmune, autoimmune polyendocrine syndrome, cancer, celiac disease, congenital adrenal hyperplasia, cortisol, dehydration, depression, diabetes mellitus, diarrhea, endocrine, fatigue, fludrocortisone, hemochromatosis, hemolysis, hormone, hyperpigmentation, hypoglycemia, hypothyroidism, imaging, irritability, kidneys, loss of appetite, loss of consciousness, low blood pressure, medical emergency, melasma suprarenale, menstrual periods, muscle weakness, nausea, numbness, orthostatic hypotension, paralysis, phosphate, physician, pituitary gland, potassium, pregnant, salt, sarcoidosis, surgery, tetany, tuberculosis, vitiligo, vomiting, weight loss
 Adapted from the Wikipedia article "Pathophysiology", under the G.N U Free Docmentation License. Please also see http://en.wikipedia.org/wiki |
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