5-MeO-DMT: Encyclopedia - 5-MeO-DMT

5-MeO-DMT

5-MeO-DMT is a very powerful psychedelic entheogen. It is found in a wide variety of plant species and has been used by South American shamans for over 1200 years.

5-MeO-DMT - Chemistry

5-MeO-DMT was first synthesized in 1936, and in 1959 it was isolated as one of the psychoactive ingredients of Anadenanthera peregrina seeds used in Yopo snuff.

5-MeO-DMT - History

Traditionally 5-MeO-DMT was used as a psychedelic snuff, such as yopo or Vilca, and is often found in small quantities in Ayahuasca brews. It is also the major ingredient of the venom of Colorado River toad (Bufo alvarius), although there is no direct evidence this was used as an entheogen until recent times.

5-MeO-DMT - Use and effects

When used as a drug in its purified form, 5-MeO-DMT is smoked, snorted, or injected and is active at a dose of as little as 2mg. The onset of effects occurs in seconds after smoking/injecting, or minutes after insufflating, and the experience is often described as similar to a Near Death Experience. It can also become orally active with the use of an monoamine oxidase inhibitor to inhibit its quick metabolism. 5Meo-DMT produces effects similar to DMT with the exception of psychedelic visuals. 5Meo-DMT when smoked produces peak effects for approximately 5-10 minutes. When 5Meo-DMT is insuffalated, the peak effects are considerably less intense than when smoked, but last for 15-25 minutes on average.

See also

Dimethyltryptamine (DMT)

Adapted from the Wikipedia article "5-MeO-DMT", under the G.N U Free Docmentation License. Please also see http://en.wikipedia.org/wiki